北京地区18所高校医院2007～2008年口服降糖药采购数据分析

目的:了解北京地区高校医院口服降糖药的应用情况及趋势。方法:对北京地区18所高校医院2007～2008年采购的零差率中标药品中口服降糖药品种、采购金额、用药频度(DDDs)、日均费用(DDC)等数据进行统计、分析。结果:α-糖苷酶抑制剂的采购金额、DDDs、DDC均排在各类口服降糖药的第1位;格列喹酮片、二甲双胍肠溶片(0.25g)的DDDs分列第2、3位,而DDC分列第5、6位。结论:α-糖苷酶抑制剂是2007～2008年北京地区高校医院口服降糖药的首选药物,但采购金额与用药人/次的同步相关性较差。格列喹酮片、二甲双胍肠溶片(0.25g)的药物利用合理性和药物经济价值较高,值得临床和患者优先选用。

Analysis of Purchasing Data of Oral Antidiabetic Agents in 18 University Hospitals in Beijing During 2007-2008

OBJECTIVE： To probe into the status quo and tendency of the utilization of oral hypoglycemic agents in university- affiliated hospitals in Beijing area. METHODS： As one of the zero-difference rate drugs that won the bid, the oral hypoglycemic drugs purchased between 2007 and 2008 by 18 university hospitals in Beijing area were analyzed statistically in respect of the drug variety, DDDs and DDC etc. RESULTS： Of all the oral hypoglycemic agents purchased, α- glycosidase inhihitors took the lead in terms of purchase sum, DDDs as well as DDC. Gliquidone Tablets ranked at the second place and metformin enteric-coated tablets（0.25 g） the third place in terms of DDDs while the DDC of the two drugs ranked at the fifth and the sixth, respectively. CONCLUSION： α- glycosidase inhibitors are the first choice drugs for patients with diabetes in university hospitals in Beijing area. However, the purchase sum and medication person - time of it showed poor synchronism. The utilization of Gliquidone Tablets and Metformin Enteric-coated Tablets（0.25 g） were rational and economicalwhich thus deserve to be used preferably in clinical practice.