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补肾益精方对切除卵巢大鼠骨质疏松模型腰椎骨生物力学性能的影响
引用本文:朱太咏,石印玉,张戈,王健智,沈培芝,赵咏芳,徐宇,史万忠.补肾益精方对切除卵巢大鼠骨质疏松模型腰椎骨生物力学性能的影响[J].中国老年学杂志,2001,21(4):301-303.
作者姓名:朱太咏  石印玉  张戈  王健智  沈培芝  赵咏芳  徐宇  史万忠
作者单位:1. 河南省洛阳正骨研究所,河南,洛阳,471002
2. 上海中医药大学附属曙光医院
3. 上海市中医药研究院骨伤科研究所
基金项目:国家中医局"95攻关"课题(96096-09-05)
摘    要:目的:探讨被 肾益精方对去卵巢大鼠骨质疏松模型松质骨生物力学性能的影响,方法:40只10月龄Wistar雌性大鼠随机分为正常对照组,模型对照组,补肾益精方组和倍美力组,每组10只,正常对照组做假手术,其余3组做卵巢切除术,术后3个月开始给药,连续用药满90天,处死,取出第3腰椎,测定其骨质含量并进行压应力测试与分析,结果:补肾益精方组比模型组腰椎骨的骨质含量提高了6.19%,最大承载力增加了21.66%,极限强度增加了16.93%,结论:应用补肾益精方可以明显改善去卵巢大鼠骨质疏松模型松质骨的生物力学性能。

关 键 词:骨质疏松  补肾益精方  生物力学  骨质含量  腰椎
文章编号:1005-9202(2001)04-0301-03
修稿时间:2000年7月20日

The effects of "MIGU JIAONANG" on biomechanics performances of the lumbovertebral bone in ovariectomized rat
ZHU Tai yong,SHI Yin yu,ZHANG Ge et al Luo Yang Bonesetting Institute of Henan Province,Henan Luoyang.The effects of "MIGU JIAONANG" on biomechanics performances of the lumbovertebral bone in ovariectomized rat[J].Chinese Journal of Gerontology,2001,21(4):301-303.
Authors:ZHU Tai yong  SHI Yin yu  ZHANG Ge Luo Yang Bonesetting Institute of Henan Province  Henan Luoyang
Institution:ZHU Tai yong,SHI Yin yu,ZHANG Ge et al Luo Yang Bonesetting Institute of Henan Province,Henan Luoyang 471002
Abstract:? Objective To explore the effects of "MIGU JIAONANG" on biomechanics performances of the lumbovertebral bone in ovariectomized rat.Methods 40 wistar female rats aged 10 months were divided into 4 groups:the normal,modelled,"MIGU JIAONANG" treated and Premarin treated.The normal group was only sham operated and other three groups were ovariectomized.Ninety one days after operation,the rats were given the medicines for 90 days and then killed,the third lumbar vertebrae were taken out,and the whole bone quantity and biomechanical properties were detemined.Results "MIGU JIAONANG" could significantly increase the whole bone quantity and improve the biomechanics properties of the lumboverterbal bone in osteoporosis rats.
Keywords:Ostepoporosis  Experimental study  "MIGU JIAONANG"  Biomechanics
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