中草药抗弓形虫作用机制的研究进展

弓形虫是一种专性细胞内寄生的机会性致病原虫， 可感染多种动物和人， 严重危害畜牧业生产和人类健康。由 于弓形虫生活史复杂， 形态各异， 致病机理繁杂， 目前尚无特效治疗和预防药物。中药具有平衡阴阳和整体调节机体免 疫力的特点， 毒副作用小， 已成为治疗弓形虫病安全有效药物的研究热点。为进一步探寻中药的抗弓形虫作用机理及治 疗效果， 本文对黄芩、 桦褐孔菌多糖、 甘草、 南瓜子和槟榔等中草药或其提取物的抗弓形虫机制及疗效等相关研究进展进 行了综述。

Advances in researches on mechanism of anti-Toxoplasma Chinese herbal medicine

Toxoplasma gondii is an opportunity cellular parasite，related to the infection of various animals and human be? ings and severely impairing agriculture and human health. Because of the complexity of T. gondii life cycle，its different biologi? cal characteristics，and multifarious pathogenesis，there are no specific treatment and preventive medicines at present. Chinese herbal medicine can balance“yin?yang”and regulate the immunity and its side?effect is slight. Now，it has been a hot topic of the research on effective and secure medicines in anti?toxoplasmosis. This paper summarizes and analyzes the curative effect and mechanism of anti?Toxoplasma Chinese herbal medicine，such as Scutellaria baicalensis，Inontus obliquus polysaccharide，Ra? dix glycyrrhizae， pumpkin seeds，and Semen arecae.