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表皮葡萄球菌在慢性鼻-鼻窦炎患者中生物膜的表达
引用本文:应华永,徐瑞龙,诸葛盼,卜黎红,杨卫仙,尤慧华. 表皮葡萄球菌在慢性鼻-鼻窦炎患者中生物膜的表达[J]. 上海医学检验杂志, 2011, 0(2)
作者姓名:应华永  徐瑞龙  诸葛盼  卜黎红  杨卫仙  尤慧华
作者单位:浙江省金华市中心医院;浙江省金华市妇幼保健院;
基金项目:浙江省卫生厅项目(2007A190); 金华市科技局项目(2007-3-032)
摘    要:目的研究表皮葡萄球菌生物膜在慢性鼻-鼻窦炎(CRS)患者鼻黏膜中的表达情况。方法将临床手术中获取的180例慢性鼻-鼻窦炎患者内镜手术黏膜样本,根据细菌培养结果将其分为4组,分别为表皮葡萄球菌生长组79例,其他葡萄球菌生长组33例,阴性杆菌生长组27例,细菌培养阴性组41例,所有样本均行标准的扫描电子显微镜方法检测。结果表皮葡萄球菌生长组79例全部观察到生物膜的存在,表达率为100%(79/79),其他葡萄球菌生长组为75.8%(25/33),阴性杆菌生长组为77.8%(21/27),细菌培养阴性组为41.5%(17/41)。后3组分别与表皮葡萄球菌组比较,P值均<0.01。结论表皮葡萄球菌在CRS患者生物膜形成中起重要作用。

关 键 词:表皮葡萄球菌  生物膜  细菌培养  慢性鼻-鼻窦炎  电镜扫描  

The expression of Staphylococcus epidermidis biofilm in patients with chronic rhinosinusitis
YING Huayong,XU Ruilong,ZHUGE Pan,BU Lihong,YANG Weixian,YOU Huihua.. The expression of Staphylococcus epidermidis biofilm in patients with chronic rhinosinusitis[J]. Shanghai Journal of Medical Laboratory Sciences, 2011, 0(2)
Authors:YING Huayong  XU Ruilong  ZHUGE Pan  BU Lihong  YANG Weixian  YOU Huihua.
Affiliation:YING Huayong1,XU Ruilong1,ZHUGE Pan1,BU Lihong1,YANG Weixian2,YOU Huihua1.(1.Jinhua Municipal Central Hospital,Zhejiang Jinhua 321000,China,2.Jinhua Maternity and Infant Health Hospital,China)
Abstract:Objective To investigate the expression of Staphylococcus epidermidis biofilm in the nasal mucosa of patients with chronic rhinosinusitis(CRS).Methods 180 samples were collected during endoscopic sinus surgery from patients with CRS.According to the results of bacterial culture,they were classified into 4 groups [Staphylococcus epidermidis growth group(79 cases),other Staphylococcus aureus growth group(33 cases),negative bacillus growth group(27 cases) and bacterial culture-negative group(41 cases)].All sam...
Keywords:Staphylococcus epidermidis  Biofilm  Bacterial culture  Chronic rhinosinusitis  Scanning electron microscopyh  
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