Habitual Sleep Duration and Insomnia and the Risk of Cardiovascular Events and All-cause Death: Report from a Community-Based Cohort |
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Authors: | Kuo-Liong Chien Pei-Chung Chen Hsiu-Ching Hsu Ta-Chen Su Fung-Chang Sung Ming-Fong Chen Yuan-Teh Lee |
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Institution: | 1.Institute of Preventive Medicine, College of Public Health, National Taiwan University;2.Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan;3.Institute of Environmental Health, College of Public Health, China Medical University;4.Institute of Clinical Medical Science, China Medical University Hospital, Taichung, Taiwan |
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Abstract: | Study Objectives:To investigate the relationship between sleep duration and insomnia severity and the risk of all-cause death and cardiovascular disease (CVD) eventsDesign:Prospective cohort studySetting:Community-basedParticipants:A total of 3,430 adults aged 35 years or olderIntervention:NoneMeasurements and Results:During a median 15.9 year (interquartile range, 13.1 to 16.9) follow-up period, 420 cases developed cardiovascular disease and 901 cases died. A U-shape association between sleep duration and all-cause death was found: the age and gender-adjusted relative risks (95% confidence interval CI]) of all-cause death (with 7 h of daily sleep being considered for the reference group) for individuals reporting ≤ 5 h, 6 h, 8 h, and ≥ 9 h were 1.15 (0.91–1.45), 1.02 (0.85–1.25), 1.05 (0.88–1.27), and 1.43 (1.16–1.75); P for trend, 0.019. However, the relationship between sleep duration and risk of CVD were linear. The multivariate-adjusted relative risk (95% CI) for all-cause death (using individuals without insomnia) were 1.02 (0.86–1.20) for occasional insomnia, 1.15 (0.92–1.42) for frequent insomnia, and 1.70 (1.16–2.49) for nearly everyday insomnia (P for trend, 0.028). The multivariate adjusted relative risk (95% CI) was 2.53 (1.71–3.76) for all-cause death and 2.07 (1.11–3.85) for CVD rate in participants sleeping ≥9 h and for those with frequent insomnia.Conclusions:Sleep duration and insomnia severity were associated with all-cause death and CVD events among ethnic Chinese in Taiwan. Our data indicate that an optimal sleep duration (7–8 h) predicted fewer deaths.Citation:Chien K; Chen P; Hsu H; Su T; Sung F; Chen M; Lee Y. Habitual sleep duration and insomnia and the risk of cardiovascular events and all-cause death: report from a community-based cohort. SLEEP 2010;33(2):177–184. |
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Keywords: | Sleep cohort study cardiovascular disease |
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