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大承气汤对家兔胃动素分泌和胃电活动影响的实验研究
引用本文:冯敬坤,岳华,李爱英,张风华,宋翠淼,曹刚. 大承气汤对家兔胃动素分泌和胃电活动影响的实验研究[J]. 河北中医药学报, 2002, 17(2): 1-3
作者姓名:冯敬坤  岳华  李爱英  张风华  宋翠淼  曹刚
作者单位:河北医科大学中医学院,石家庄,050091
摘    要:目的:观察大承气汤(DT)经胃给药对家兔胃动素分泌和胃电活动的影响。方法:用DT给家兔经胃给药,分别观察30、90、210min胃动素分泌和胃电活动结果。结果:给药后30min,胃动素分泌和胃电活动均受到明显抑制;给药后90min胃动素水平仍低于给药前,但呈上升趋势,而胃电活动已恢复至给药前水平且呈逐渐加强趋势;给药后210min胃动素水平超过给药前,胃电活动则明显增强。结论:DT经胃给药对家兔胃动素分泌和胃电活动均有先抑制后促进的作用。

关 键 词:大承气汤 胃动素 胃电 家兔 中药 药理
文章编号:1007-5615(2002)02-0001-03
修稿时间:2002-04-23

Experimental Research on the Effect of Dachengqitang on Rabbits Motilin Secretion and Electrogastroaction
Physiology Teaching and Research Section,Hebei Medical University FENG Jing-kun YUE Hua LI Ai-ying et al. Experimental Research on the Effect of Dachengqitang on Rabbits Motilin Secretion and Electrogastroaction[J]. Journal of Hebei Traditional Chinese Medicine and Pharmacology, 2002, 17(2): 1-3
Authors:Physiology Teaching  Research Section  Hebei Medical University FENG Jing-kun YUE Hua LI Ai-ying et al
Affiliation:Shijiazhuang 050091
Abstract:Objective: To observe the effect of Dachengqitang (DT) on rabbits motilin secretion and elec-trogastroaction with dosing stomach. Method: To dose rabbits with DT and observe respectively the results of motilin secretion and electrogastroaction after 30, 90 and 210 minutes. Results; 30 min after dosing, its motilin secretion and electrogastroaction were obviously inhibited; 90 min later, the level of motilin was below that before dosing with a rising trend, and electrogastroaction restored to the level before. dosing with a strengthening trend; 210 min later, the level of motilin exceeded that before dosing while the electrogastroaction were obviously strengthened. Conclusion: DT, after being dosed to stomach, can inhibit and then accelerate rabbits motilin secretion and electrogastroaction.
Keywords:Dachengqitang (DT)  motilin  gastric electricity  rabbit
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