| 酸枣仁皂苷D的分离及结构鉴定 |
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| 引用本文： | 刘沁舡,王邠,梁鸿,赵玉英,刘孟军.酸枣仁皂苷D的分离及结构鉴定[J].药学学报,2004,39(8):601-604. |
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| 作者姓名： | 刘沁舡 王邠 梁鸿 赵玉英 刘孟军 |
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| 作者单位： | 1. 北京大学,药学院,天然药物学系,北京,100083
2. 河北农业大学,园艺学院,河北,保定,071001 |
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| 基金项目： | 国家重点科技项目 ( 99 92 9 0 1 3 4) |
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| 摘 要： | 目的研究酸枣仁Ziziphus jujuba Mill var. Spinosa (Bunge) Hu ex. H.F.的化学成分。方法用多种色谱方法分离化学成分、鉴定结构。结果从正丁醇部分分离得到5个化合物，其结构分别为：酸枣仁皂苷D(1, jujuboside D)，酸枣仁皂苷A(2, jujuboside A)，5,7,4′-三羟基黄酮醇-3-O-β-D-鼠李糖(1→6)-β-D-葡糖苷(3), 5,4′-二羟基-7-甲氧基黄酮-6-C-6-对香豆酰基-β-D-葡萄糖(1→2)-β-D-葡糖苷(4, 6-coumaroylspinosin)及苯丙氨酸(5)。结论化合物1为新化合物，化合物4作为阻转异构体存在为首次报道，化合物3和5为首次从酸枣仁获得。
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| 关 键 词： | 酸枣仁 酸枣仁皂苷D 化学成分 |
| 收稿时间： | 2003-10-08 |
Structure identification of jujuboside D |
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| LIU Qin-xiang,WANG Bin,LIANG Hong,ZHAO Yuying,LIU Meng-jun.Structure identification of jujuboside D[J].Acta Pharmaceutica Sinica,2004,39(8):601-604. |
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| Authors: | LIU Qin-xiang WANG Bin LIANG Hong ZHAO Yuying LIU Meng-jun |
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| Institution: | Division of Natural Medical Chemistry, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China. |
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| Abstract: | AIM: To study the chemical constituents of Ziziphus jujuba Mill var. Spinosa (Bunge) Hu ex. H. F. Chou. METHODS: To separate the constituents by using various kinds of chromatography and identify their structures on the basis of spectral analysis. RESULTS: Five compounds were isolated and their structures were established as jujuboside D (1), jujuboside A (2), 5,7,4'-trihydroxyflavonol-3-O-beta-D-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (3), 6'-coumaroylspinosin (4) and phenylalanine (5). CONCLUSION: Compound 1 is a new compound named jujuboside D, 4 is reported as rotamer for the first time, 3 and 5 isolated from this plant for the first time. |
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| Keywords: | Ziziphus jujuba Mill var Spinosa jujuboside D chemical constituents |
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