Relationship between free-radical lipid oxidation and efficiency of coronary angioplasty in coronary patients |
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| Authors: | A I Kaminnyi V Z Lankin E I Perepelitsa G G Konovalova A N Samko A K Tikhaze V V Kukharchuk Yu N Belenkov |
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| Institution: | (1) A. L. Myasnikov Institute of Cardiology, Russian Cardiological Center, Russian Ministry of Health, Moscow |
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| Abstract: | Low-dose (250 mg daily) oral probucol produces a significant antioxidant effect in coronary patients: increases activity of
glutathione peroxidase (enzyme utilizing lipoperoxides) and reduces the content of free-radical oxidation products in the
blood. Probucol therapy for 7 days before and for 6 months after coronary angioplasty significantly reduces the severity of
coronary artery stenosis.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 11, pp. 503–506, November, 2007 |
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| Keywords: | transluminal coronary angioplasty restenosis thrombosis inflammation antioxidants |
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