Sjögren's Syndrome with Pleural Effusion: Difficult to Distinguish from Tuberculous Pleurisy Because of a High Adenosine Deaminase Level |
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| Authors: | Masafumi Shimoda Yoshiaki Tanaka Kozo Morimoto Kiyomi Shimoda Tamiko Takemura Teruaki Oka Takashi Yoshiyama Kozo Yoshimori Ken Ohta |
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| Affiliation: | 1.Respiratory Disease Center, Fukujuji Hospital, Japan Anti-tuberculosis Association, Japan; 2.Department of Thoracic Surgery, Fukujuji Hospital, Japan Anti-tuberculosis Association, Japan; 3.Department of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan; 4.Department of Pathology, Fukujuji Hospital, Japan Anti-tuberculosis Association, Japan |
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| Abstract: | An 84-year-old woman visited our hospital for dyspnea due to right pleural effusion, with lymphocytic dominance and a high adenosine deaminase (ADA) level, that had been noted 1 month earlier. She was suspected of having tuberculosis pleurisy; however, anti-tuberculosis treatment yielded no improvements. She was diagnosed with pleural effusion due to primary Sjögren''s syndrome (SjS) based on her dry eyes and mouth, positivity for anti-Sjögren''s-syndrome-related antigen A/B, and histopathologic findings of a lip biopsy and thoracoscopic pleural biopsy. Her symptoms improved after starting steroid therapy. Cases of pleural effusion due to SjS with a high ADA level may be misdiagnosed as tuberculosis pleurisy. |
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| Keywords: | Sjö gren''s syndrome, pleural effusion, adenosine deaminase, tuberculous pleurisy |
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