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Unilateral pseudouveitis revealing a pancreatic neuroendocrine carcinoma: A case report
Authors:Faten Cherchir  Ines Naceur  Ahmed Anas Haouari  Tayssir Ben Achour  Hajer Ben Mansour  Khadija Bellil  Fatma Said  Mohamed Habib Houman
Affiliation:1. Department of Internal Medicine, La Rabta University Hospital, University of Tunis El Manar, Tunis Tunisia ; 2. Department of Medical Oncology, Salah Azaiez Institute, University of Tunis El Manar, Tunis Tunisia ; 3. Department of Anatomic Pathology, La Rabta University Hospital, University Tunis El Manar, Tunis Tunisia
Abstract:Neuroendocrine tumors are a heterogeneous group of tumors with a wide range of malignant potential that tend to have a relative prolonged course. These tumors infrequently metastasize to the orbit. To the best of our knowledge, ocular metastases from pancreatic neuroendocrine tumors (PNETs) have never been reported in the literature. We report the case of a 61‐year‐old man who presented with progressive deterioration of general condition with unilateral recurrent episodes of non‐granulomatous panuveitis of the left eye related to a choroidal metastasis. Radiological imaging and histopathological analyses led to the diagnosis of metastatic pancreatic neuroendocrine carcinoma as the primary tumor. Choroidal metastases from neuroendocrine tumors are extremely rare, but compromise patients’ well‐being because of visual impairment. Uncommonly, these metastases can be the first manifestation of unknown tumors, warranting further investigations to detect the primary cancer.
Keywords:carcinoma   choroidal   metastasis   neuroendocrine   pancreatic   pseudouveitis   tumors
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