Detection and characterization of HIV type 2 in Calcutta, India |
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| Authors: | Bhanja Payel Mandal Dibya Kanti Jana S Bhattacharya S K Chakrabarti S |
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| Affiliation: | National Institute of Cholera and Enteric Diseases, Calcutta, India. |
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| Abstract: | Since the first report of HIV/AIDS in India in 1986, continuous serosurveillance has been undertaken in all Indian states. Recently, five cases of HIV-2 infection have been detected in Calcutta, situated in the eastern part of India. The full-length envelope gene (2.5 kb) of one of the strains was amplified, cloned, and sequenced. Phylogenetic analysis of the Calcutta HIV-2 envelope revealed a close relatedness to the HIV-2 Rod sequence isolated in offshore Senegal. This strain, however, showed a genetic diversity of 13.5% to other Indian HIV-2 isolates. |
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