| 健脾化湿颗粒的制备工艺研究 |
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| 引用本文： | 杜建平,施之琪,江志强.健脾化湿颗粒的制备工艺研究[J].药学与临床研究,2011,19(5):478-480. |
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| 作者姓名： | 杜建平 施之琪 江志强 |
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| 作者单位： | 1. 广东省中医研究所,广州,510095
2. 广州中医药大学,广州,510405 |
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| 摘 要： | 目的:研究健脾化湿颗粒的制备工艺。方法:以干膏得率和芍药苷得率作为评价指标,采用L9(34)正交试验法优选健脾化湿颗粒的提取工艺;以颗粒吸湿性和成型性为指标,对干法制粒的工艺进行研究。结果:最佳提取工艺为:加10倍水,回流提取2次,每次2h;干压法制备得到的颗粒吸湿性和成型性好。结论:优选的健脾化湿颗粒工艺稳定可行,可应用于工业化生产。
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| 关 键 词： | 健脾化湿颗粒 正交设计 制备工艺 |
| 收稿时间： | 2011/8/30 0:00:00 |
| 修稿时间： | 2011/9/10 0:00:00 |
Preparation Technology of Spleen-invigorating and Dampness-resolving Granule |
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| DU Jian-ping,SHI Zhi-qi and JIANG Zhi-qiang.Preparation Technology of Spleen-invigorating and Dampness-resolving Granule[J].Pharmacertical and Clinical Research,2011,19(5):478-480. |
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| Authors: | DU Jian-ping SHI Zhi-qi and JIANG Zhi-qiang |
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| Institution: | DU Jian-ping1,SHI Zhi-qi1,JIANG Zhi-qiang2 1Guangdong Provincial Institute of Traditional Chinese Medicine,Guangzhou 510095,2Guangzhou University of Chinese Medicine,Guangzhou 510405,China |
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| Abstract: | Objective: To optimize the preparation process of Spleen-invigorating and Dampness-resolving Granule.Methods: The optimal extraction of Spleen-invigorating and Dampness-resolving Granule was investigated by the L9(34) orthogonal experiment.With hydroscopicity,and formability as the indexes,the dry granulating process was evaluated.Results: The optimal extraction procedures were as follows: adding 10-fold water,refluxing extraction for 2 times(2 hours per time).The hydroscopicity and formability of the granu... |
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| Keywords: | Spleen-invigorating and Dampness-resolving Granule Orthogonal design Preparation technology |
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