结直肠腺癌肠镜活检组织病理诊断分析

目的分析结、直肠癌内窥镜活检组织腺癌的病变特点，总结临床病理特征，提高活检诊断率。方法通过切片HE染色对238例腺癌标本进行组织学分析，按照WHO诊断标准，必须存在黏膜肌层浸润到黏膜下层的特点诊断为结、直肠癌，并于手术根治切除标本病理诊断相对比，活检部分病例进行免疫组化标记aetin、desmine、SMA确定平滑肌组织。结果1441例活检标本中238例诊断为腺癌，其中153例行根治性切除，其中62例（40．5％）活检不能肯定浸润黏膜下层，腺瘤癌变局限在黏膜内3例，浸润肌层5例。结论结、直肠腺癌活检组织对不确定浸润黏膜下层的病例不使用黏膜内瘤变，事实上这些病例绝大多数是浸润性癌。内窥镜及外科医生多取材、深取材，与病理医生多沟通是提高诊断的有效途径。

Analysis of pathological diagnosis for biopsy of colorectal carcinoma

Objective To analyze the clinical pathologica diagnosis for biopsy of colorectal adenocarcinoma,increase the rate of biopsy diagnosis.Methods Two hundred and thirty-eight cases of colorectal adenocarcinoma specimens histological analysis.According to the WHO criteria for diagnosis must muscularis mucosa,there was infiltration into the submucosa characteristics for the diagnosis of colorectal cancer,surgery and removal of pathology specimens compared.Part of the biopsy cases IHC actin,desmine,SMA determine t...