双歧杆菌对脾虚小鼠肠道菌群的调整作用

目的：观察双歧杆菌对大黄致脾虚小鼠肠道菌群的调整作用。方法：大黄致脾虚造模型法和粪菌群定量检测法，结果：在大黄造模组小鼠肠道菌群中，双歧杆菌、类杆菌和乳酸杆菌的数量下降，大肠杆菌的数量上升（P＜0.05），经灌服双歧杆菌制剂（108／ml，1ml/天）一周后，以上各菌群数量恢复正常。结论：服用双歧杆菌制剂有改善机体牌虚证的作用。

The Regulative Role of Bifidobacterium in the Intestinal Flora of Spleen Insuffciency Mice

To observe the regulative role of Bifidobacterium in the intestinal flora ofspleen insufficiency mice. Methods The mice model of spleen insufficiency were established by oral administration of Daihuang (Rheum palmatum) decoction . The counts of fecal flora were determined.Results The counts of Bifidobacterium, Bacteroides and Lactobacillus, were decreased and E. coli wasincreased in the feces of spleen insufficiency mice (P<0. 05). After the mice ingested B. bifidum (108/ml) for one week, 1ml/day, the counts Of fecal flora were restored to normal level. ConclusionBifidobactrium possesses the effects of adjusting the intestinal flora of mice and promting the recoveryof the mice with spleen insufficiency.