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多焦视皮质诱发电位检查对白内障患者术后视力的预测(英文)
引用本文:由彩云,刘平,高维奇. 多焦视皮质诱发电位检查对白内障患者术后视力的预测(英文)[J]. 国际眼科杂志, 2009, 9(6): 1016-1019. DOI: 10.3969/j.issn.1672-5123.2009.06.002
作者姓名:由彩云  刘平  高维奇
作者单位:1. 青岛大学医学院,中国山东省青岛市,266021
2. 哈尔滨医科大学第一临床医院眼科,中国黑龙江省哈尔滨市,150001
摘    要:目的:评价术前多焦视皮质诱发电位(multifocal visual evoked potential,mVEP)检查对白内障术后视力的预测价值。方法:随机选取白内障患者共52例60眼,其中老年性白内障27例30眼,合并青光眼的白内障25例30眼(青光眼均为慢性闭角型缓解期或慢性进行期),术前对其行mVEP检查,另取正常对照组30眼。所有患者均行超声乳化联合折叠人工晶状体植入术。患者于术后1wk;1,3mo复查最佳矫正视力(best corrected visual acuity,BCVA)。结果:正常对照组mVEP检测平均主波振幅和潜伏期分别是183±11nV、95±8ms,老年性白内障组平均主波振幅和潜伏期分别是177±10nV、96±8ms,2组在统计学上无显著性差异(P>0.05);合并青光眼的白内障组平均主波振幅和潜伏期分别是138±7nV、99±6ms,与正常对照组及老年性白内障组均存在显著性差异(P<0.05);白内障超声乳化联合人工晶状体植入术后BCVA≥0.8者,无明显眼底视功能改变,其mVEP中心位点主波振幅276±11nV和潜伏期93±8ms与正常对照组无显著性差异(P>0.05);而术后BCVA<0.3者,眼底视功能检查有明显改变(术后检查证实),其mVEP中心位点主波振幅221±6nV,潜伏期105±7ms,与正常对照组差异显著(P<0.05)。结论:白内障术前mVEP振幅和潜伏期的改变可用来客观判断眼底视功能损害及预测术后视力。术前mVEP正常者高度提示术后视力预后良好,而mVEP检查结果变化显著,提示伴有眼底视功能损害,术后BCVA差。因此术前mVEP检查可作为预测白内障术后视力的一种有效、客观的检查方法。

关 键 词:多焦视皮质诱发电位  白内障  最佳矫正视力

Prediction of multifocal visual evoked potential for postoperative visual recovery in cataract patients
Cai-Yun You,Ping Liu,Wei-Qi Gao. Prediction of multifocal visual evoked potential for postoperative visual recovery in cataract patients[J]. International Eye Science, 2009, 9(6): 1016-1019. DOI: 10.3969/j.issn.1672-5123.2009.06.002
Authors:Cai-Yun You  Ping Liu  Wei-Qi Gao
Affiliation:Cai-Yun You1,Ping Liu2,Wei-Qi Gao21Qingdao University Medical College,Qingdao 266071,Shandong Province,China2Department of Ophthalmology,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China
Abstract:AIM: To determine multifocal visual evoked potential (mVEP) in the prediction of postoperative visual acuity in cataract. METHODS: We examined 30 normal eyes as control and 60 eyes of 52 cataract patients, senile cataract in 27 cases 30 eyes, cataract with glaucoma in 25 cases 30 eyes by mVEP examination. All patients underwent phacoemulsifi-cation (Phaco) and intraocular lens (IOL) implantation. After surgery,best corrected visual acuity (BCVA) was examined at 1 week, 1 month, and 3 months respectively.RESULTS: The mean amplitude and latency in mVEP responses between normal control group were 183±11nV, 95±8ms, and in senile cataract group were 177±10nV, 96± 8ms respectively, there were no significant difference between two groups (P>0.05). The mean amplitude and latency of cataract with glaucoma 138±7nV, 99±6ms were significantly different comparing to both control and senile cataract group (P<0.05). After surgery, the am-plitude and latency were 276±11nV and 93±8ms respec-tively, which did not change significantly comparing to the normal eyes (P<0.05), their visual function got no obvious damage and visual recovery were better (BCVA≥0.8). While those with central amplitude 221±6nV and latency 105±7ms that were significantly deviated from control group (P<0.05), and their visual function were seriously damaged and visual recovery were much poorer (BCVA<0.3).CONCLUSION: mVEP waveform might enable us to evaluate objective visual function detection before cataract surgery. A subject with visual function damage, their mVEP responses to stimulation were severely changed when it compared to controls.
Keywords:multifocal visual evoked potential  cataract  best corrected visual acuityDOI:10.3969/j.issn.1672-5123.2009.06.002
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