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COPD患者外周血几项免疫指标的变化
引用本文:袁开芬,赵国厚,杨建华,张国粹.COPD患者外周血几项免疫指标的变化[J].昆明医学院学报,2001,22(1):59-60.
作者姓名:袁开芬  赵国厚  杨建华  张国粹
作者单位:昆明医学院第二附属医院干疗科,
摘    要:为了探讨COPD患者外周血可溶性白细胞介素2受体(sIL-2R)、白细胞介素-8(IL-8)、免疫球蛋白、T淋巴细胞亚群水平变化,用ELISA法检测COPD患者30例,对照组30例,血清sIL-2R,IL-8;免疫散射速率法测IgG,IgA;单克隆抗体免疫组化萤光染色法测CD^ 3,CD^ 4,CD^ 8,并进行分析。结果COPD患者sIL-2R,IL-8,CD^ 8增高;IgG,IgA,CD^ 3,CD^ 4,CD^ 4/CD^ 8比值均降低,具有较显著性差异,提示COPD患者免疫功能低下。

关 键 词:COPD  sIL-2R  IL-8  免疫球蛋白  T淋巴细胞亚群  细胞因子  慢性阻塞性肺疾病
文章编号:1003-4706(2001)01-0059-02
修稿时间:2000年12月6日

Study the Variety of Serum Interleukin-2 Receptor, Interleukin-8, Immunoglobulin, T-lymphyocyte Subgroup in Patients with COPD
YUAN Kai-fen,ZHAO Guo-hou,YANG Jian-hua,ZHANG Guo-cui.Study the Variety of Serum Interleukin-2 Receptor, Interleukin-8, Immunoglobulin, T-lymphyocyte Subgroup in Patients with COPD[J].Journal of Kunming Medical College,2001,22(1):59-60.
Authors:YUAN Kai-fen  ZHAO Guo-hou  YANG Jian-hua  ZHANG Guo-cui
Abstract:To study the variety of sIL-2R, Il-8, immunoglo bulin, T-lymphycyte subgroup in patients with COPD. 30 cases with COPD and the control group of 30 cases were d etected sIL-2R, IL-8 with ELISA; IgG, IgA with rate nephelometry; CD + 3,CD + 1, Cd + 3,with immunoflu orescence. Results: Patients with CO-PD sIL-2R, Il-8, CD 8 increase and IgG, IgA, CD + 3, CD + 4,CD + 4/CD + 8 decrease. The difference is very significant. Conclusion: The immuni faction of patients with COPD reduce.
Keywords:COPD sIL-2R  Il-8  Immunoglobulin  T-lymphyocyte subgroup  Cell factor
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