2007-2008年度山东省流感监测资料分析

目的]了解山东省流感流行特点，掌握流感病毒优势毒株的变异动态，为及早发现和控制疫情提供科学依据。方法]2007年10月至2008年3月，山东省各哨点医院报告的门诊流感样病例（ILI）和门急诊病例就诊总数统计资料和部分医院采集的ILI鼻咽拭子标本流感病毒检测资料进行分析。结果]监测期间，全省52家哨点医院合计，内科（儿内科）门诊病例1267783例，其中ILI23023例，占1.82％。ILI％，2007年10月至2008年3月分别为1．79％、1．68％、1．87％、2．18％、1．88％、1．50％（P〈0．05）；55．72％的ILI集中在5岁以下年龄组；不同地区ILI就诊百分比不同，滨州市、潍坊市、泰安市分别为5．30％、3．88％、3．37％，菏泽市、临沂市、德州市分别为0．17％、0．34％、0．53％，其他11个市为0．56％～2．97％。合计检测ILI标本941份，检出流感病毒246株（H1N1型3株，H3N2型114株，B型124株，H3N2型和B型混合感染5株）。阳性率为26．14％。流感病毒检测阳性率，各月分别为18．60％、15．57％、28．81％、36．20％、17．43％、17．46％（P〈0．05）。结论]2007～2008年度山东ILI疫情平稳，以H3N2和B型为优势流行株。

Analysis of Influenza Surveillance in Shandong Province from 2007 to 2008

Objective]To understand the pattern of influenza incidence and influenza viral variation in Shandong,and to provide scientific basis for early detection and control of its epidemic. Methods]From October 2007 to March 2008,Influ- enza-like illness data was filled in web-based-forms by monitoring hospitals, and throat and nasal swabs were collected from influenza-like illness in monitoring hospitals for influenza virus separation with Madin Darby Canine Kidney （MD- CK） cell line and for identification of Influenza virus type with hemagglutination inhibition test. Results]Epidemiological and laboratory surveillance showed that,during that period,influenza-like illness accounted for 1.82 % of the total outpatients（23 023 out of 1 267 783）. From Otc. 2007 to Mar. 2008,the ILI% of each month was 1.79%, 1.68%, 1.87%, 2.18 %, 1.88 %, 1.50%, respectively（ P 〈0. 05） ;55. 72 % of ILI was among children aged 0-5 years. The ILI % was significantly different in different cities, 5.30 % in Binzhou, 3.88 % in Weifang, 3.37 % in Taian, 0.17 % in Heze, 0.34 % in Linyi,0. 53% in Dezhou,and from 0.56 % to 2.97 % in the other cities. Positive rate of influenza virus was 26.14 % （246 strains out of 941 specimens）. From October 2007 to March 2008, the rate of the positive specimens of each month was 18.60%, 15.57%, 28.81%, 36.20%, 17.43%, 17.46%, respectively （ P 〈 0.05） . Of the positive specimens, 124 （ 50.41% ） were influenza B viruses, 114 （46.34 % ） influenza A（H3） viruses, 5 （2.03 % ） influenza B and influenza A（ H 3） mixed infection, and 3（1.22 % ）were influenza A（H1）viruses. Conclusion]Influenza was not prevalent in Shandong during 2007-2008 influenza season. Etiological surveillance revealed that influenza H3H2 and B was the predominant epidemic strain. The peak of ILI is in accordance with the peak of virus isolated.