2005～2007年郑州市腹泻患者志贺菌监测结果分析

目的]了解郑州市志贺菌的菌型分布,为防控菌痢流行提供可靠数据。方法]按照《全国细菌性痢疾监测工作方案》对郑州市市辖医院20052007年腹泻患者粪便标本进行志贺菌分离培养、生化鉴定和血清学分型以及药敏试验。结果]20052007年郑州市共检测1 321份标本,检出志贺菌116株,检出率为8.78%。志贺菌分布在福氏和宋內氏2个群,未检出A群和C群。不同年份间菌株均以B群志贺菌为主,分别为39、37和21株,分别占当年阳性菌株的92.86%、77.08%、80.77%;福氏志贺菌以F4c（47株）为主,占48.45%,其次是F1a（21株）、F2a（17株）,分别占21.65%和17.53%;志贺菌对萘啶酸和四环素100.00%耐药。结论]各年优势菌群均为福氏志贺菌,F4c为优势菌型,多种菌型并存,临床治疗要根据耐药情况合理使用抗生素。

Analysis of Monitoring Results for Shigella for Diarrhea Cases in Zhengzhou City from 2005 to 2007

Objective]To provide reliable data for preventing prevalence of bacillary dysentery,understanding the distribution of Shigella type in Zhengzhou city.Methods]According to the＂Project for Surveillance of Shigellosis in China＂,the detection,isolation,identification and sensitivity test for Shigella to diarrhea specimens of patients were performed from 2005 to 2007.Results]116 strains of Shigella were isolated from 1 321 diarrhea cases from 2005 to 2007（8.78%）.Neither group A nor group C was detected.Between different years,group B was mainly of Shigella,39,37 and 21 stains from 2005 to 2007,and in positive strains were 92.86%,77.08%,80.77%,respectively.Serotype was F4c mainly（48.45%）,followed by F1a（21.65%） and F2a（17.53%）.Nalidixic acid and tetracycline were 100.00% drug resistant.Conclusion]F4c was the predominant bacteria type annual.Clinical treatment should be based on the rational use of antibiotic resistance.