| 注射用甲磺酸加替沙星细菌内毒素检查法研究 |
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| 引用本文： | 田静,姚治.注射用甲磺酸加替沙星细菌内毒素检查法研究[J].中国现代应用药学,2008,25(6):545-547. |
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| 作者姓名： | 田静 姚治 |
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| 作者单位： | 1. 杭州市第六人民医院,杭州,310014
2. 浙江省食品药品检验所,杭州,310004 |
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| 摘 要： | 目的建立注射用甲磺酸加替沙星细菌内毒素检测方法。方法用不同厂家的鲎试剂对不同批号的注射用甲磺酸加替沙星分别进行干扰试验,考察确立注射用甲磺酸加替沙星细菌内毒素检测方法。结果注射用甲磺酸加替沙星稀释液500μg.mL-1、83.3μg.mL-1对细菌内毒素检测无干扰。结论注射用甲磺酸加替沙星可用细菌内毒素检查方法取代家兔热原检查法。
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| 关 键 词： | 注射用甲磺酸加替沙星 细菌内毒素 鲎试剂 |
The Bacterial Endotoxins Test of Gatifloxacin Mesylate for Injection Experimental Study |
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| TIAN Jing,YAO Zhi.The Bacterial Endotoxins Test of Gatifloxacin Mesylate for Injection Experimental Study[J].The Chinese Journal of Modern Applied Pharmacy,2008,25(6):545-547. |
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| Authors: | TIAN Jing YAO Zhi |
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| Abstract: | OBJECTIVE To study the bacterial endotoxin test for gatifloxacin mesylate for injection using tachypleus amebocyte lysate.METHODS By interfering test,the inhibition/enhancement action of gatifloxacin mesylate for injection with limulus lysate was studied. |
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| Keywords: | gatifloxacin mesylate for injection tachypleus amebocyte lysate bacterial endotoxin test |
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