| 一氧化氮合酶在听源性惊厥易感大鼠室旁核的变化 |
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| 引用本文： | 高华善,于恩华.一氧化氮合酶在听源性惊厥易感大鼠室旁核的变化[J].神经解剖学杂志,1998,14(3):255-257. |
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| 作者姓名： | 高华善 于恩华 |
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| 作者单位： | 北京医科大学解剖学系!北京，100083，滨州医学院解剖学教研室，山东滨州，256603，北京医科大学解剖学系!北京，100083，北京医科大学解剖学系!北京，100083，北京医科大学解剖学系!北京，100083 |
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| 摘 要： | 用NADPH-d组织化学方法，观察和比较了室旁核内一氧化氮合酶在听源性惊厥易感大鼠和正常Wistar大鼠下丘脑室旁核的分布和变化.结果显示：在惊厥发作的大鼠，室旁核内一氧化氮合酶阳性神经元的光密度值明显高于非惊厥发作的听源性惊厥易感大鼠和正常Wistar大鼠。提示室旁核内的一氧化氮可能参与了惊厥应答过程。
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| 关 键 词： | 一氧化氮合酶 听源性惊厥 室旁核 大鼠 |
CHANGE OF NITRIC OXIDE SYNTHASE IN THE PARAVENTRICULAR NUCLEUS OF THE AUDIOGENIC SEIZURES SUSCEPTIBLE RATS |
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| Gao Huashan, Yu Enhua, Shen Li, Xu Luxi.CHANGE OF NITRIC OXIDE SYNTHASE IN THE PARAVENTRICULAR NUCLEUS OF THE AUDIOGENIC SEIZURES SUSCEPTIBLE RATS[J].Chinese Journal of Neuroanatomy,1998,14(3):255-257. |
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| Authors: | Gao Huashan Yu Enhua Shen Li Xu Luxi |
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| Abstract: | The NADPH-diaphorase histochemical method was used to study the distribution and change of nitric oxide synthase (NOS) in the hypothalamic paraventricular nucleus (PVN) of the audiogenic seizure susceptible (P77PMC ) rats and northal Wistar rats. The results indicated that the P77PMC rats with seizure presented the highest optic density value of NOS positive neurons in PVN, as compared with the P77PMC rats without seizure and normal Wistar rats. These suggested that nitric oxide in PVN might have a role in response to seizure. |
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| Keywords: | NOS audiogenic seizures paraventricular nucleus rat |
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