家兔主要大脑动脉胆碱能神经与蝶腭神经节、耳神经节的关系

应用神经节切除术和胆碱酯酸级化法，对19只新西兰家兔大脑前、中、后动脉的胆碱能神经的形态学变化进行了比较观察，目的在于探明主要的大脑动脉胆碱能神经与蝶腭神经节、耳神经节的关系．根据两组动物实验（①非手术组：不切除神经节，只对大脑前、中、后动脉进行胆碱酯酶染色，作为正常对照之用；②手术组：按五组不同组合方式，分别切除神经书，然后进行胆碱酯酶染色，观察不同方式的切除手术后的胆碱能神经的变化）的结果证明：非手术组的各主要大脑动脉壁上均存在丰富的棕红色胆碱能神经纤维，主干及分支都清晰可见，神经纤维密度呈（+++）．手术组各种方式的切除神经节的结果，表现为出现胆碱酯酶聚积现象和神经纤维的分布密度降低（++、+），未发现神经纤维消失．本研究的结果又提示，家兔一侧的主要大脑动脉胆碱能神经的节后神经元可能与双侧的蝶腭神经节和耳神经节有关。

THE RELATIONSHIP BETWEEN CHOLINERGIC NERVES ON ARTERIES OF THE BASE OF THE BRAIN AND SPHENOPALATINE/OTIC GANGLIA IN RABBITS

In order to study the relationship between cholinergic nerves and spheno-palatine ganglion(SPG) /otic ganglion, the morphorology of cholinergic nerves on arteries of the base of the brain in 19 New Zealand rabbits were divided into 3 groups.Group I (non-operation group): the main arteries of the base of the brain of 2 rabbits were treated with AChE technique. Group II (operation group); 5 kinds of operation were performed on 15 rabbits, including the removal of unilateral or bilateral SPG on 6 rabbits, of unilateral or bilateral otic ganglia on 6 rabbits, of unilateral SPG and otic ganglion on 3 rabbits. All rabbtits were killed in 6～14 days after ganglionectomy and treated with AChE technique, Group, (contr0l group); anti-AChE agent was added in the reaction solution when corresoonding arteries of 2 rabbits was treated with AChE technique. The results showed that the clear main trunk and branches of brown red cholinergic nerve fibers with the highest-density (m) on the wall of the arteries were observed in group I. In group Ⅱ, accumulation of cholinesterase was found and the density of fibers was decreased to and+. However, the cholinergic nerves could not be seen in the control group. The above results suggest that the bodies of postganglionic neurons of cholinergic nerve on unilateral major arteries of the base of the brain may be related to bilateral sphenopalatine and otic ganglia.