| 罗氏海盘车中一个新的神经酰胺-罗氏神经酰胺A |
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| 引用本文： | 詹永成,裴月湖,孙吉佑,许兴友. 罗氏海盘车中一个新的神经酰胺-罗氏神经酰胺A[J]. 中国海洋药物, 2006, 25(6): 31-32 |
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| 作者姓名： | 詹永成 裴月湖 孙吉佑 许兴友 |
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| 作者单位： | 1. 淮海工学院海洋生物技术实验室,江苏,连云港,222005
2. 沈阳药科大学中药学院,辽宁,沈阳,110016 |
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| 基金项目： | 江苏省自然科学基金(No.BK2005045)，淮海工学院生物技术开放课题资助 |
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| 摘 要： | 目的研究海洋生物罗氏海盘车(Asterias rollestoniBell)的化学成分。方法采用硅胶柱色谱、凝胶柱色谱、制备HPLC等手段,利用理化和波谱分析方法,对罗氏海盘车中的化学成分进行了分离鉴定。结果与结论分离鉴定了1个神经酰胺类化合物:(2S,3S,4R)-2-(13’-甲基十五碳酰胺)-十九碳-1,3,4-三醇,该化合物为未见文献报道的新化合物,命名为罗氏神经酰胺A。
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| 关 键 词： | 药物化学 罗氏海盘车 罗氏神经酰胺A |
| 文章编号： | 1002-3461（2006）06-0031-02 |
| 收稿时间： | 2006-05-26 |
| 修稿时间： | 2006-05-26 |
A novel ceramide from starfish Asterias rollestoni Bell-rollceramide A |
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| ZHAN Yong-cheng,PEI Yue-hu,SUN Ji-you,XU Xing-you. A novel ceramide from starfish Asterias rollestoni Bell-rollceramide A[J]. Chinese Journal of Marine Drugs, 2006, 25(6): 31-32 |
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| Authors: | ZHAN Yong-cheng PEI Yue-hu SUN Ji-you XU Xing-you |
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| Affiliation: | 1. Lab. Of Marine Biotechnology , Huaihai Institute of Technology, Lianyungang 222005, China ; 2. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China |
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| Abstract: | Objective To study the chemical constituents of starfish Asterias rollestoni Bell.Methods The constituents were isolated by chromatography methods and identified by spectroscopic and chemical analyses.Results and Conclusion A novel compound was obtained and identified as(2S,3S,4R)-2-(13'-methyl-pentadecanoylamino)-nondecane-1,3,4-triol.The compound was reported first time and named as rollceramide A. |
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| Keywords: | medicinal chemistry Asterias rollestoni Bell rollceramide A |
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