系统性红斑性狼疮脉络膜视网膜炎吲哚菁绿血管造影表现:随访一例

目的:用眼底荧光血管造影(fundus fluorescein angiography,FFA)和吲哚菁绿血管造影(indo-cyaninegreenangiography,ICGA)随访一例系统性红斑性狼疮(systemic lupuseryth ematosus,SLE)脉络膜视网膜炎患者。方法:回顾性研究随访1例SLE脉络膜视网膜炎患者临床和眼底造影影像学特征。结果:本病例ICGA特征包括造影早期脉络膜血管模糊弥漫性高荧光、局灶性低荧光,造影晚期点状脉络膜高荧光。经泼尼松治疗后,造影晚期点状脉络膜点状高荧光随着视网膜小血管阻塞出现而增加,当视网膜出现新生血管时点状高荧光消失。结论:ICGA可以揭示SLE脉络膜病变临床和FFA不能发现的信息。免疫复合物沉积在脉络膜毛细血管可能是SLE脉络膜炎发病机制的重要因素。

Indocyanine Green Angiographic Findings of Systemic Lupus Erythematosus Choroidopathy:A Follow-up Study of One Patient

Purpose: To report a follow-up study of one patient with systemic lupus erythematosus (SLE) choroidopathy studied with fluorescein angiography (FA) and indocyanine green angiography (ICGA). Methods: Retrospective review of clinical and photographic records of a patient with SLE choroidopathy. Results: ICGA findings observed in this patient included fuzziness of large choroidal vessels in the early phase, diffuse zonal choroidal hyperfluorescence in the posterior pole and well-defined pinpoint spots of choroidal hyperfluorescence in posterior pole in the late phase. In particular, the pinpoint spots of choroidal hyperfluorescence increased with the occurrence of small arterial occlusion in the retina and disappeared with the emergence of retinal neovascularization. Conclusions: ICGA can reveal information that is not detectable by clinical or FA in patients of SLE choroidopathy. The immune complex deposition in the choriocapillaries may have played a role in the pathogenesis of SLE choroidopathy.