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Evaluating regional blood spinal cord barrier dysfunction following spinal cord injury using longitudinal dynamic contrast-enhanced MRI |
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| Authors: | Ilkan Tatar Peter Cheng-te Chou Mohamed Mokhtar Desouki Hanaa El Sayed Mehmet Bilgen |
| Affiliation: | (1) Preclinical Imaging in Translational Research Laboratory, Radiology and Radiological Science, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA;(2) Pathology, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA;(3) Neuroscience, Medical University of South Carolina, 169 Ashley Avenue, Charleston, SC 29425, USA |
| Abstract: | BackgroundIn vivo preclinical imaging of spinal cord injury (SCI) in rodent models provides clinically relevant information in translational research. This paper uses multimodal magnetic resonance imaging (MRI) to investigate neurovascular pathology and changes in blood spinal cord barrier (BSCB) permeability following SCI in a mouse model of SCI. |
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