| 皂苷类成分抗肿瘤活性的研究进展 |
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| 引用本文： | 单磊,张卫东,张川,苏娟,柳润辉,周耘. 皂苷类成分抗肿瘤活性的研究进展[J]. 中草药, 2005, 36(2): 295-298 |
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| 作者姓名： | 单磊 张卫东 张川 苏娟 柳润辉 周耘 |
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| 作者单位： | 第二军医大学药学院,上海,200433 |
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| 基金项目： | 国家863项目(2003AA2Z3507)，上海市科技发展基金资助项目(02DZ19147,01DJ19010) |
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| 摘 要： | 皂苷类成分在自然界分布广泛、资源丰富,许多皂苷具有良好的抗肿瘤活性,而且其抗肿瘤机制复杂多样,因此皂苷作为天然抗肿瘤药物具有很大的研究价值和开发前景。综述了皂苷的抗肿瘤活性和作用机制,及皂苷目前在临床作为抗肿瘤药物的应用情况,通过对皂苷抗肿瘤作用机制的系统阐述,为皂苷抗肿瘤的进一步药理研究、构效关系研究以及开发应用提供参考。
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| 关 键 词： | 皂苷 抗肿瘤活性 构效关系 |
| 文章编号： | 0253-2670(2005)02-0295-04 |
| 收稿时间： | 2004-05-12 |
Advances in research on antitumor activity of saponins from plants |
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| SHAN Lei,ZHANG Wei-dong,ZHANG Chuan,SU Juan,LIU Run-hui and ZHOU Yun. Advances in research on antitumor activity of saponins from plants[J]. Chinese Traditional and Herbal Drugs, 2005, 36(2): 295-298 |
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| Authors: | SHAN Lei ZHANG Wei-dong ZHANG Chuan SU Juan LIU Run-hui ZHOU Yun |
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| Affiliation: | School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | |
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| Keywords: | saponins antitumor activity structure-activity relationship |
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