MRI表观弥散加权系数对SS腮腺异常的评价

目的:初步探讨MRI表观弥散加权系数在判断舍格伦综合征(SS)腮腺异常中的价值。方法:选取12例SS患者(病例组)和12例志愿者(对照组)作为研究对象。通过弥散加权成像(DWI)技术获取表观弥散加权系数(ADC)图,经Functool软件分析得到每组腮腺的ADC值,分别用配对样本和独立样本t检验对每组及组间腮腺ADC值进行统计分析。结果:病例组和对照组两侧腮腺的ADC均值分别为(1.047±0.515)×10-3mm2/sec、(1.087±0.426)×10-3mm2/sec和(0.682±0.107)×10-3mm2/sec、(0.652±0.153)×10-3mm2/sec,经配对样本t检验无明显差异;两组全部腮腺的ADC均值分别为(1.067±0.462)×10-3mm2/sec,(0.667±0.130)×10-3mm2/sec,经独立样本t检验两组间ADC存在明显差异,提示在SS患者腮腺中水分子有较少的限制性弥散。结论:通过DWI得到的ADC值可能有助于观察SS患者腮腺异常。

The evaluation of abnormality of parotid glands with SS using apparent diffusion coefficient for MRI.

Objective： To discuss preliminarily the value of apparent diffusion coefficient （ADC） for magnetic resonanceimaging （MRI） in evaluating abnormality of parotid glands with Sjiogren syndrome （SS）. Method： 12 patients with SS （case group） and 12 volunteers （control group） were selected for this study. Original diffusion-weighted imaging （DWI） im- ages were dealed with Functool software for ADC maps and ADC values in each group and intergroup were analysed by Paired-Samples and Independent-Samples T Test, respectively. Result： The mean ADC for both parotid glands in the case and control group was （1.047：t：0.515） × 10-3 mm2 / sec, （1.087±0.426） × 10-3 mm2 / sec and （0.682±0.107）× 10-3 mm2 / sec, （0.652±0.153）X l0-z mm2 /sec,respectively. There was no significant difference between ADC for both parotid glands in each group by Paired-Samples T Test. The combined mean ADC for both parotid glands in both groups was （1.067± 0.462） × 10-3 romE/ sec, （0.667±0.130）× 10-3 mm2/see,respectively. There was significant difference for the mean ADC intergroup, which was analysed by Independent-Samples T Test （P 〈0.05） and suggested there is less restricted diffusion：in parotid glands affected by SS. Conclusion： These results suggest that ADC obtained by DWI may contribute to detect parotid abnormalities in patients with SS.