首页 | 本学科首页   官方微博 | 高级检索  
     

疏肝化癥方对小鼠皮下移植性三阴性乳腺癌生长的抑制作用及其机制
引用本文:王博,杨焱,费瑞,景年财,李兆东,卢义,肖宏宇,张越. 疏肝化癥方对小鼠皮下移植性三阴性乳腺癌生长的抑制作用及其机制[J]. 吉林大学学报(医学版), 2021, 47(2): 299-306. DOI: 10.13481/j.1671-587X.20210207
作者姓名:王博  杨焱  费瑞  景年财  李兆东  卢义  肖宏宇  张越
作者单位:长春中医药大学中医学院中医内科,吉林 长春 130117
吉林省肿瘤医院中西医结合科,吉林 长春 130012
吉林大学基础医学院细胞生物学系,吉林 长春 130021
基金项目:吉林省科技厅科技发展计划项目
摘    要:目的:探讨疏肝化癥方对乳腺癌小鼠的抑瘤作用及其对肿瘤血管生成的影响,并阐明其可能的作用机制.方法:将40只雌性BALB/c小鼠随机分为模型组和0.01、0.10、1.00及10.00 g·kg-1疏肝化癥方组,每组8只.采用小鼠腋下胸骨前缘乳腺脂肪垫内接种4T1细胞法构建三阴性乳腺癌(TNBC)小鼠模型.模型构建成功后...

关 键 词:疏肝化癥方  三阴性乳腺癌  血管生成  血管内皮生长因子  血管生成素样蛋白2
收稿时间:2020-08-15

Inhibitory effect of Shuganhuazheng Formula on growth of triple negative breast cancer of subcutaneous transplantation in mice
WANG Bo,YANG Yan,FEI Rui,JING Niancai,LI Zhaodong,LU Yi,XIAO Hongyu,ZHANG Yue. Inhibitory effect of Shuganhuazheng Formula on growth of triple negative breast cancer of subcutaneous transplantation in mice[J]. Journal of Jilin University: Med Ed, 2021, 47(2): 299-306. DOI: 10.13481/j.1671-587X.20210207
Authors:WANG Bo  YANG Yan  FEI Rui  JING Niancai  LI Zhaodong  LU Yi  XIAO Hongyu  ZHANG Yue
Affiliation:Department of Internal Medicine of Chinese Medicine,College of Chinese Medicine,Changchun University of Chinese Medicine,Changchun 130117,China
Department of Integrated Traditional Chinese and Western Medicine,Jilin Tumor Hospital,Changchun 130021,China
Department of Cell Biology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China
Abstract:ObjectiveTo investigate the anti-tumor effect of Shuganhuazheng Formula and the influence in the tumor angiogenesis in the mice with breast cancer, and to clarify its posible mechanism.
Keywords:Shuganhuazheng Formula  triple negative breast cancer  angiogenesisa  vascular endothelial growth factor  angiogenic protein-2  
本文献已被 万方数据 等数据库收录!
点击此处可从《吉林大学学报(医学版)》浏览原始摘要信息
点击此处可从《吉林大学学报(医学版)》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号