| 羟氯喹在IgA肾病中的应用 |
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| 引用本文： | 肖永真,杨晓. 羟氯喹在IgA肾病中的应用[J]. 临床肾脏病杂志, 2021, 21(3): 253-257 |
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| 作者姓名： | 肖永真 杨晓 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院肾内科,武汉430022 |
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| 摘 要： | IgA肾病是全世界范围内最常见的肾小球疾病,根据改善全球肾脏病预后组织治疗IgA肾病指南推荐,肾素-血管紧张素-醛固酮系统抑制剂(renin-angiotensin-aldosterone sys-tem inhibitors,RAASi)的应用能有效减少IgA肾病的蛋白尿及控制血压,从而延缓疾病的进展.临床上糖皮质激...
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| 关 键 词： | 羟氯喹 IgA肾病 免疫 蛋白尿 |
Application of hydroxychloroquine for IgA nephropathy |
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| Xiao Yong-zhen,Yang Xiao. Application of hydroxychloroquine for IgA nephropathy[J]. Journal Of Clinical Nephrology, 2021, 21(3): 253-257 |
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| Authors: | Xiao Yong-zhen Yang Xiao |
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| Affiliation: | (Department of Nephrology,Affiliated Union Hospital,Tongji Medical College,Huazhong University of Science&Technology,Wuhan 430022,China) |
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| Abstract: | Globally IgA nephropathy has been the most common glomerular disease.According to the guidelines of Kidney Disease:Improving Global Outcomes(KDIGO)for treating IgA nephropathy,renin-angiotensin-aldosterone system inhibitors(RAASi)may effectively alleviate proteinuria and control blood pressure,thereby significantly delaying the progression of the disease.Glucocorticoids or immunosuppressants are routinely applied.Hydroxychloroquine(HCQ)is an immunomodulatory agent for malaria and autoimmune diseases.Recent studies have demonstrated that HCQ was efficacious for persistent proteinuria in patients with IgA nephropathy.The relevant literature reports were retrieved for comprehensively reviewing the application characteristics of HCQ for IgA nephropathy. |
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| Keywords: | Hydroxychloroquine IgA nephropathy Immunity Proteinuria |
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