发育性髋关节发育不良发病危险因素的研究进展

发育性髋关节发育不良(developmental dysplasia of the hip,DDH)是小儿骨科常见的下肢发育畸形,严重危害患者及其家长身心健康。影响DDH发病的因素可大致分为两部分,即遗传因素和环境因素。随着20世纪80年代高检出率髋关节超声的应用及国家二胎政策的开放,可预见未来一段时期内DDH患者数量将会增加。早诊断、早治疗是该病国内外公认的诊治原则,0~6月龄更是其治疗的黄金时期。但目前其发病的确切病因、发病机制尚不完全清楚,因此对婴儿进行早期筛查和及时干预,对早期诊治意义重大。笔者通过简要综述发育性髋关节发育不良发病危险因素的研究进展,以期为DDH早期筛查和诊断提供参考。

Research advances for risk factors of developmental dysplasia of the hip

As a common developmental deformity of lower extremity in pediatric orthopedics,developmental dysplasia of the hip(DDH)seriously endangers physical and mental health of children and their families.There are many risk factors of genetic and environmental origins.With rapid developments of high-detection-rate hip ultrasound in 1980s and a new national policy of fostering a second child,it may be predicted that the number of DDH Children'shall spike in the future.Early diagnosis and treatment are generally established principles at both home and abroad and age of 0-6 months has been an optimal window of interventions.However,the exact etiology and pathogenesis of DDH have remained elusive.Therefore it is of great importance for the early diagnosis and treatment of DDH by early screening and timely intervention of risk factors with predictive value.Here the latest research advances of risk factors of DDH were summarized for providing practical references for its early screening and diagnosis.