核医学肾脏显像对儿童肾积水患者分肾功能的评估价值

核医学肾脏显像包括肾动态显像和肾静态显像.利尿肾动态显像如应用于儿童肾积水患者,在评估分肾功能的同时,可协助判断尿路梗阻的性质.由于婴儿肾脏肾小球发育不成熟,建议行肾动态显像时,＜2岁患者使用肾小管分泌型显像剂99mTc-双半胱氨酸(99mTc-EC),＞2岁者使用肾小球滤过型显像剂99mTc-喷替酸(99mTc-DT...

Value of nuclear medicine renal imaging in the assessment of renal function in pediatric hydronephrosis

In nuclear medicine,renal scan includes renal dynamic and static imaging.Diuretic renal dynamic imaging is recommended for pediatric hydronephrosis.It evaluates the nature of hydronephrosis while assessing differential renal function.Different radiotracers are utilized for renal dynamic scan of pediatric hydronephrosis.According to age,^99mTc-EC is recommended for children aged under 2 years and ^99mTc-DTPA for those aged over 2 years.When analyzing renal function and renogram curve,clinicians should pay attention to various influencing factors.Glomerular filtration rate(GFR)based upon double plasma method is accurate.However,wider clinical applications are difficult.Based upon renal dynamic imaging,many influencing factors for GFR require comprehensive analyses.Renal static imaging is employed for evaluating the extent and severity of pyelonephritis and renal scar.Also renal function may be evaluated.There are fewer influencing factors of renal static imaging.With recent widespread applications of single photon emission computed tomography/computed tomography(SPECT/CT)in nuclear medicine,^99mTc-DMSA SPECT/CT tomography can more accurately assess the kidney function of pediatric hydronephrosis.This review discussed the uses of nuclear medicine renal imaging in evaluating renal function in pediatric hydronephrosis.