血流向量成像技术定量评估慢性肾脏病患者左室功能的临床价值

目的 应用血流向量成像(VFM)技术分析慢性肾脏病患者左室能量损耗(EL)变化,探讨其评估慢性肾脏病患者左室功能受损的临床价值.方法 选取慢性肾脏病患者61例,其中左室射血分数(LVEF)≥50％者42例(A组),LVEF<50％者19例(B组),另选取38例健康成人为正常对照组.应用VFM技术获取各组左室充盈早期、左...

Quantitative assessment of left ventricular function in patients with chronic kidney disease by vector flow mapping

Objective To analyze the change characteristics of left ventricular energy loss(EL)in chronic kidney disease by vector flow mapping(VFM)technique,and to explore the clinical value of EL in quantitative evaluating left ventricular function in patients with chronic kidney disease.Methods Sixty-one patients with chronic kidney disease were selected in this study,including 42 patients with left rentricular ejection fraction(LVEF)≥50%in group A,19 patients with LVEF<50%in group B,38 healthy adults were enrolled as control group.Left ventricle average EL in early filling phase(E-EL-ave),atrial filling phase(A-EL-ave),isovolumic contraction period(I-EL-ave),and ejection phase(Ej-EL-ave)were acquired and calculated by VFM technique,and the differences of above parameters in each group were compared.Receiver operating characteristic curve was drawn to analyze the diagnostic efficacy of different degrees of left ventricular dysfunction.The relationship between EL in each phase and conventional ultrasound parameters were analyzed.Results Compared with the control group,EL in all phases of group A were increased,A-EL-ave was increased in group B,and Ej-EL-ave was decreased in group B.The differences were statistically significant(all P<0.05).Ej-EL-ave showed a biphasic trend in the control group,group A and group B.Ej-EL-ave had good diagnostic efficacy for early left ventricular function impairment and LVEF<50%in patients with chronic kidney disease(area were 0.907,0.861,respectively,both P<0.001).Ej-EL-ave was positively correlated with LVEF in the patients with chronic kidney disease(r=0.636,P<0.01).Conclusion The parameter of Ej-EL-ave measured by VFM technique can be used as a potential new indicator to evaluate the efficiency of left ventricular pump function in patients with chronic kidney disease,which has certain clinical value.