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胆道闭锁Kasai手术后综合管理
引用本文:乔奇.胆道闭锁Kasai手术后综合管理[J].临床小儿外科杂志,2021,20(2):133-139.
作者姓名:乔奇
作者单位:中国医科大学附属盛京医院新生儿外科 辽宁省沈阳市,110003
基金项目:国家自然科学基金(编号:81270437);辽宁科技厅项目(编号:2017225014)。
摘    要:胆道闭锁(biliary atresia,BA)是婴儿期肝内外胆管进行性炎症及肝纤维化的疾病,其病因及疾病进展机制尚不清楚.Kasai手术(Kasai portoenterostomy,KPE)是治疗胆道闭锁的首选术式,成功的Kasai手术能够重建胆汁引流,但Kasai手术后长期自体肝生存(native liver s...

关 键 词:胆道闭锁/外科学  胆管炎/并发症  外科手术

Comprehensive managements after Kasai portoenterostomy for biliary atresia
Institution:(Department of Neonatal Surgery,Affiliated Shengjing Hospital,China Medical University,Shenyang 110004.)
Abstract:Biliary atresia(BA)is a disease of progressive inflammation and fibrosis of intra/extrahepatic bile ducts in infants.Its etiology and mechanism of progression have remained ill elucidated.Kasai portoenterostomy(KPE)is a first choice for biliary atresia.Successful KPE operation may reconstruct bile drainage.However,the long-term native liver survival(NLS)after KPE operation is relatively low and children often suffer from various complications.Most children require liver transplantation before adulthood.Comprehensive managements after KPE have great impact on NLS and long-term quality of life of children.And how to improve postoperative managements is vital for the prognosis of BA.
Keywords:Biliary Atresia/SU  Cholangitis/CO  Surgical Procedures  Operative
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