| 肝细胞癌早期诊断中的生物标志物 |
| |
| 引用本文： | 刘熙称,王艺颖,童曼曼,秦俊杰. 肝细胞癌早期诊断中的生物标志物[J]. 临床肝胆病杂志, 2021, 0(1): 176-179 |
| |
| 作者姓名： | 刘熙称 王艺颖 童曼曼 秦俊杰 |
| |
| 作者单位： | 吉林大学第一医院肝胆胰内科;吉林大学第一医院急诊内科 |
| |
| 摘 要： | 晚期肝细胞癌(HCC)患者预后通常较差,如若能早期诊断,并采取行之有效的治疗措施则可显著提高患者生存率。目前,AFP是检测HCC应用最广泛的血清标志物。然而,在一些HCC患者中并未发现AFP的升高。分析了AFP、乙型肝炎核心相关抗原、液体活检技术、微小RNA、长链非编码RNA及外泌体在HCC早期诊断中的应用潜力,通过探讨其研究进展,为HCC早期诊断方法的探索提供依据。
|
| 关 键 词： | 癌,肝细胞 早期诊断 生物标记,肿瘤 |
Biomarkers for the early diagnosis of hepatocellular carcinoma |
| |
| LIU Xichen,WANG Yiying,TONG Manman,QIN Junjie. Biomarkers for the early diagnosis of hepatocellular carcinoma[J]. Chinese Journal of Clinical Hepatology, 2021, 0(1): 176-179 |
| |
| Authors: | LIU Xichen WANG Yiying TONG Manman QIN Junjie |
| |
| Affiliation: | (Department of Hepatology,The First Hospital of Jilin University,Changchun 130021,China;Department of Emergency Internal Medicine,The First Hospital of Jilin University,Changchun 130021,China) |
| |
| Abstract: | Patients with advanced hepatocellular carcinoma(HCC)often have poor prognosis,and early diagnosis and effective treatment measures can significantly improve the survival rate of patients.At present,alpha-fetoprotein(AFP)is the most widely used serum marker for the diagnosis of HCC in the world;however,no increase in AFP was found in some HCC patients.This article analyzes the application potential of AFP,hepatitis B core-related antigen,liquid biopsy technology,microRNA,long non-coding RNA,and exosomes in the early diagnosis of HCC and reviews related research advances,so as to provide a basis for exploring new methods for the early diagnosis of HCC. |
| |
| Keywords: | Carcinoma,Hepatocellular Early Diagnosis Biomarkers,Tumor |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
