099mTc—MIBI硝酸异山梨酯介入显像对冠脉支架置入术后心肌血流灌注的评估

目的：探讨99mTc锝-甲氧基异丁基异腈（99mTc—methoxyisobutyl isonitrile，Tc—MIBI）评估冠状动脉支架置入术（支架置入术）后损伤区心肌细胞血流灌注状况的价值。方法：40例行支架置入术患者，分别在置入术前、后进行99mTc—MIBI心肌静态显像及其硝酸异山梨酯（ISDN）介入显像，对比分析损伤区心肌细胞血流灌注改善程度。结果：40例患者冠状动脉共有360个节段。术前Tc—MIBIISDN介入显像异常10g个节段（29．2％），显著少于Tc—MIBI静态显像异常的178个节段（49．4％，P〈0．01）。支架置入术后ISDN介入显像异常91个（25．3％）节段也显著少于静态显像异常的112个节段（31．1％，P〈0．05）。结论：99mTc—MIBI—ISDN介入显像较99mTc—MIBI心肌静态显像更能反映支架置入术后心肌血流灌注情况。

Value of 99mTc-MIBI and its isosorbide dinitrate myocardial imaging on evaluated myocardial blood flow perfusion after intracoronary stenting

Objective： To study the value of 99mTc--MIBI and its isosorbide dinitrate myocardial imaging on evaluated myocardial blood flow perfusion after intracoronary stenting. Methods： A total of 40 cases with 360 coronary seg- ments were study by 99mTc-- methoxy isobutyl isonitrile （99m Tc--MIBI） rest imaging and its isosorbide dinitrate （IS- DN） involving imaging before and after operation. The imaging of blood flow perfusion in myocardial cells between a- bove stated two methods. Results： Before intracoronary stenting, the abnormal segments were 109 （29.2%） in 99mTc --MIBI ISDN involving imaging, it was significantly less than that of 99m Tc--MIBI imaging during rest （178 seg- ments, 49.4%） ; after intracoronary stenting, the abnormal segments were 91 （25.3%） in 99mTc--MIBI ISDN invol- ving imaging, it was significantly less than that of 99mTc--MIBI imaging during rest （112 segments, 31.1%）, P〈 0.05 all. Conclusion： Fore reflect myocardial blood flow perfusion, 99mTc--MIBI ISDN involving imaging is better than 99mTc--MIBI myocardial rest imaging.