Effects of specific antibodies on the ultrastructure of mouse oocytes |
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| Authors: | M. Sh. Verbitskii Ya. N. Gotsulyak |
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| Affiliation: | (1) Laboratory of Immunomorphology of Human Reproduction, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow;(2) Department of Immunology and Cytotoxic Sera, A. A. Bogomolets Institute of Physiology, Ukrainian Academy of Sciences, Kiev |
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| Abstract: | The effects of antiovarian antiserum and monoclonal antibodies to the oolemma antigens on the ultrastructure of mouse oocytes and their microenvironment are studied. The antioolemma monoclonal antibodies cause more pronounced degenerative changes in the oocyte that in its microenvironment. Antiovarian antiserum induces greater changes in the microenvironment than in the oocyte. Changes induced in the oocyte by the antiserum are secondary relative to changes occurring in the microenvironment, while changes observed in the oocyte treated with monoclonal antibodies are primary. Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 1, pp. 115–119, January, 1997 |
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| Keywords: | oocyte pellucid zone monoclonal antibodies |
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