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抗白细胞介素靶向治疗支气管哮喘临床应用研究进展
引用本文:施浩,杨悦,方伟,徐红卫. 抗白细胞介素靶向治疗支气管哮喘临床应用研究进展[J]. 中国医药导报, 2011, 8(36): 19-20
作者姓名:施浩  杨悦  方伟  徐红卫
作者单位:1. 广东省汕头市龙湖人民医院呼吸内科,广东汕头,515041
2. 广东省汕头市龙湖人民医院检验科,广东汕头,515041
3. 广东省汕头市龙湖疾病控制中心慢病控制科,广东汕头,515041
摘    要:支气管哮喘的经典病理、生理学研究认为,引起哮喘的主要病理学改变主要是由于支气管的平滑肌发生痉挛及肥大。世界卫生组织(WHO)在关于哮喘病的免疫脱敏治疗中明确指导并指出:免疫脱敏治疗是根治过敏性疾病的唯一治疗方法。本文研究分析利用细胞因子中白细胞介素(IL-1、IL-2、IL-4、IL-5、IL-13、IL-33等)作为靶点进行靶向治疗支气管哮喘的临床应用及其进展。

关 键 词:支气管哮喘  平滑肌发生痉挛  免疫脱敏治疗  白细胞介素

Clinical research progress of anti-interleukin-targeted in the treatment of bronchial asthma
SHI Hao,YANG Yue,FANG Wei,XU Hongwei. Clinical research progress of anti-interleukin-targeted in the treatment of bronchial asthma[J]. China Medical Herald, 2011, 8(36): 19-20
Authors:SHI Hao  YANG Yue  FANG Wei  XU Hongwei
Affiliation:SHI Hao1,YANG Yue1,FANG Wei2,XU Hongwei3 1.Department of Respiratory Medicine,Longhu People's Hospital of Shantou City,Guangdong Province,Shantou 515041,China,2.Department of Laboratory,3.Department of Chronic Disease Control,Longhu Disease Control Center of Shantou City
Abstract:Classic pathology physiological studies of bronchial asthma suggest that the main pathological changes caused by asthma mainly due to bronchial smooth muscle spasm and hypertrophy.In the treatment of asthma in the immune desensitization,world health organization(WHO) has clearly guided that immune desensitization therapy is the only cure for allergic diseases treatment.This paper analyzes cytokines interleukin(IL-1,IL-2,IL-4,IL-5,IL-13,IL-33,etc.) used as targeted,and its clinical application and progress i...
Keywords:Bronchial asthma  Smooth muscle spasm  Immune desensitization therapy  Interleukin  
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