| 乳腺癌术后患者血清癌胚抗原，糖类抗原15—3与^99Tc^m-亚甲基二膦酸盐全身骨扫描结果分析 |
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| 引用本文： | 曾小明.乳腺癌术后患者血清癌胚抗原，糖类抗原15—3与^99Tc^m-亚甲基二膦酸盐全身骨扫描结果分析[J].中国医药导报,2011,8(31):112-113. |
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| 作者姓名： | 曾小明 |
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| 作者单位： | 江苏省太仓市第一人民医院核医学科,江苏太仓,215400 |
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| 摘 要： | 目的：探讨癌胚抗原（CEA）与糖类抗原15—3（CAl5—3）联合检测对^99Tc^m-亚甲基二膦酸盐（MDP）全身骨扫描诊断乳腺癌骨转移特异性价值的影响。方法：对78例乳腺癌患者分别进行CEA、CAl5—3检测及^99Tc^m-MDP全身骨扫描检查．并选择30例健康人群者作为对照组进行比较。结果：全身骨转移组CEA与CAl5—3检测结果较对照组显著上升（P〈0．01）。1—3处放射性浓聚灶组CEA与CAl5—3检测结果均较对照组上升（P〈0．05、P〈0．01）。无骨转移组CEA与CAl5—3检测结果与对照组比较，差异无统计学意义（P〉0．05）。各组CEA与CAl5—3检测阳性率比较。对照组均为0，全身骨转移组CEA与CAl5—3检测阳性率（65．6％和68．8％）与对照组比较，差异有高度统计学意义（P〈0．01）；1～3处放射性浓聚灶组CEA与CAl5—3检测阳性率（29．2％和16．7％）与对照组比较，差异有统计学意义（P〈0．05、P〈0．01）；无骨转移组CEA与CAl5—3检测结果检测阳性率（9．1％和4．5％）与对照组比较，差异无统计学意义（P〉0．05）。结论：在行全身骨显像的同时，联合检测CEA、CAl5—3水平能提高骨显像的特异性，减少误诊，特别是病灶孤立或较少时意义更大。
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| 关 键 词： | 乳腺癌 全身骨扫描 癌胚抗原 糖类抗原15—3 |
Analysis of serum CEA, CA15-3 levels and 99Tcm-MDP whole body bone scanning breast cancer after operation |
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| ZENG Xiaoming.Analysis of serum CEA, CA15-3 levels and 99Tcm-MDP whole body bone scanning breast cancer after operation[J].China Medical Herald,2011,8(31):112-113. |
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| Authors: | ZENG Xiaoming |
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| Institution: | ZENG Xiaoming Department of Nuclear Medicine,the First People′s Hospital of Taicang City,Jiangsu Province,Taicang 215400,China |
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| Abstract: | Objective: To explore the value of combined detection of carcinoembryonic antigen(CEA) and carbohydrate antigen 15-3(CA15-3) for diagnosis of breast cancer by 99Tcm-MDP(MDP) whole body bone scanning.Methods: 78 cases of patients with breast cancer received 99Tcm-MDP for whole body bone scanning and CEA,CA15-3 detection.And 30 cases of health people were selected as control group.Results: The results of CEA,CA15-3 in the systemic bone metastasis group increased compared with control group(P<0.01).The results... |
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| Keywords: | Breast cancer Whole body bone scanning CEA CA15-3 |
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