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Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and D
Authors:Schmidt-Chanasit Jonas  Bleymehl Karoline  Schäd Susanne G  Gross Gerd  Ulrich Rainer G  Doerr Hans Wilhelm
Affiliation:Jonas Schmidt-Chanasit, Karoline Bleymehl, Susanne G. Schäd, Gerd Gross, Rainer G. Ulrich, and Hans Wilhelm Doerr
Abstract:Here, we describe the association of certain varicella-zoster virus (VZV) genotypes with unique glycoprotein E (gE) gene mutations. Within 45 analyzed VZV wild-type strains of genotypes A and D, five novel gE mutations were discovered. A statistically significant (P < 0.0001) association of certain gE mutations with VZV genotype D was found.
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