Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and D |
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Authors: | Schmidt-Chanasit Jonas Bleymehl Karoline Schäd Susanne G Gross Gerd Ulrich Rainer G Doerr Hans Wilhelm |
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Affiliation: | Jonas Schmidt-Chanasit, Karoline Bleymehl, Susanne G. Schäd, Gerd Gross, Rainer G. Ulrich, and Hans Wilhelm Doerr |
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Abstract: | Here, we describe the association of certain varicella-zoster virus (VZV) genotypes with unique glycoprotein E (gE) gene mutations. Within 45 analyzed VZV wild-type strains of genotypes A and D, five novel gE mutations were discovered. A statistically significant (P < 0.0001) association of certain gE mutations with VZV genotype D was found. |
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