| 心钠素在豚鼠耳蜗蜗管外壁的分布 |
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| 引用本文： | 陈合新 邱建华. 心钠素在豚鼠耳蜗蜗管外壁的分布[J]. 临床耳鼻咽喉头颈外科杂志, 1997, 11(7): 294-295 |
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| 作者姓名： | 陈合新 邱建华 |
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| 作者单位： | 第一军医大学南方医院耳鼻咽喉科!广州510515(陈合新)，西安第四军医大学西京医院耳鼻咽喉科(邱建华，乔莉，王锦玲) |
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| 摘 要： | 采用免疫组织化学ＡＢＣ法检测心钠素在正常豚鼠耳蜗外壁的分布。结果表明，在耳蜗１－４回蜗管外壁的血管纹，螺旋凸，外沟细胞及前庭附中间阶外壁的螺旋韧带均发现有ＡＮＰ反应阳性产物，即有ＡＮＰ存在；而鼓阶外壁的螺旋韧带ＡＮＰ－ＩＲ为阴性，即无ＡＮＰ存在。提示耳蜗蜗管外壁ＡＮＰ对内耳淋巴液的生成可能起着重要的作用；虽然螺旋韧带组织结构相同，但由于ＡＮＰ的分布不同其生理功能则各异。
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| 关 键 词： | 心钠素 分布 豚鼠 耳蜗 螺旋韧带 免疫组织化学 |
Immunohistochemical distribution of atrial natriuretic peptides in the external wall of cochlear duct of guinea pigs |
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| Chen Hexin, Qiu Jianhua, Qiao Li,et al. Immunohistochemical distribution of atrial natriuretic peptides in the external wall of cochlear duct of guinea pigs[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 1997, 11(7): 294-295 |
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| Authors: | Chen Hexin Qiu Jianhua Qiao Li et al |
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| Affiliation: | Nanfang Hospital, First Military Medical University, Guangzhou. |
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| Abstract: | The paper presents the distribution of the atrial natriuretic peptides(ANP) in the external wall of each turn of the cochlear duct of guinea pigs by an immunohistochemical technique (ABC method). ANP immunoreactivity (ANP-IR) was found in the strial vasculayis,sprial prominence,cells of external suicus and sprial ligament of the external wall of the vestibular canal and media canal. But no positive immunoreactive products were found in the spiral ligament of the external wall of scala tympanity. The results suggest that ANP of the external wall of the cochlear duct may play an important role in the formation of endolymphe. ANP-IR was difference in spiral ligament of in these scala. But their physiological function was different. |
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| Keywords: | Atrial natriuretic peptides Guinea pig Cochlear Sprial ligament Immunohistochemisty |
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