血液透析联合血液灌流治疗重度急性有机磷农药中毒35例临床观察

目的探讨血液透析(HP)联合血液灌流(HD)治疗重度急性有机磷农药中毒患者的疗效。方法将69例重度急性有机磷农药中毒患者随机分成治疗组与对照组2组,治疗组在常规内科治疗的基础上采用血液透析与血液灌流联合治疗,对照组在常规内科治疗基础上给予血液灌流治疗。结果治疗组昏迷至清醒时间、胆碱酯酶活力恢复时间、住院时间均较对照组明显缩短(p<0·05或0·01),而治愈率较对照组明显升高(p<0·01)。结论应用HD联合HP治疗重度急性有机磷农药中毒可明显缩短住院时间,提高治愈率。

Clinical Observation of 35 Cases with Severe Acute Organophosphorus Pesticide Poisoning Treated with Combination of Hemodialysis and Hemoperfusion

Objective To explore the curative effect of patients with severe acute organophosphorus pesticide poisoning(AOPP) by means of combined treatment of hemodialysis (HD)and hemoperfusion(HP). Methods 69 patients with severe AOPP were at random divided into two groups,The treatment group was treated with combined HD and HP with routine therapy, The control group was only treated with HP and routine therapy. Results The time of patients regaining consciousness, cholinesterase resuming and hospitalization in the treatment group were shorter than that in the control group(p<0.05). And the cure rate in the treatment group was higher than that in the control group(p< 0.01). Conclusions For the patients with severe AOPP, combined treatment of HD and HP may short the time of hospitalization and improve the cure rate.