| 蝉翼藤根中的一个新二苯酮 |
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| 引用本文： | 张丽杰,张琳,徐丽珍,杨学东,邹忠梅,杨世林. 蝉翼藤根中的一个新二苯酮[J]. 药学学报, 2005, 40(6): 536-538 |
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| 作者姓名： | 张丽杰 张琳 徐丽珍 杨学东 邹忠梅 杨世林 |
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| 作者单位： | 中国医学科学院、中国协和医科大学,药用植物研究所,北京,100094 |
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| 摘 要： | 目的对蝉翼藤(Securidaca inappendiculata Hassk.)根的二苯酮成分进行分离和结构鉴定。方法通过硅胶和凝胶反复柱色谱分离得到二苯酮类化合物；利用多种波谱技术鉴定其化学结构。结果分离鉴定了2个二苯酮化合物，其结构分别为2-甲氧基-3,4-亚甲二氧基-二苯酮(I)，4-羟基-2,6-二甲氧基-二苯酮(II)。结论化合物I为新化合物，命名为蝉翼藤二苯酮B；化合物II为首次自该属植物中分离得到。
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| 关 键 词： | 蝉翼藤 二苯酮 蝉翼藤二苯酮B |
| 收稿时间： | 2005-03-02 |
A new benzophenone from the root of Securidaca inappendiculata |
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| ZHANG Li-jie,ZHANG Lin,XU Li-zhen,YANG Xue-dong,ZOU Zhong-mei,YANG Shi-lin. A new benzophenone from the root of Securidaca inappendiculata[J]. Acta pharmaceutica Sinica, 2005, 40(6): 536-538 |
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| Authors: | ZHANG Li-jie ZHANG Lin XU Li-zhen YANG Xue-dong ZOU Zhong-mei YANG Shi-lin |
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| Affiliation: | Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China. |
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| Abstract: | Aim To study the benzophenones in the roots of Securidaca inappendiculata Hassk.. Methods Column chromatography (including silica gel and Sephadex LH-20) was used to isolate benzophenones whose structures were elucidated by HREI-MS, NMR (1D and 2D) methods. Results A new benzophenone was isolated and identified as 2-methoxy-3,4-methylenedioxy-benzophenone (I), along with a known compound 4-hydroxy-2,6-dimethoxy-benzophenone (II). Conclusion Compound I is a new one named as securiphenone B, compound II was isolated from the genus for the first time. |
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| Keywords: | Securidaca inappendiculata benzophenone securiphenone B |
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