鲍曼不动杆菌的院内感染分布及耐药性分析

目的了解鲍曼不动杆菌的院内感染分布特征及耐药趋势,为临床治疗提供参考。方法统计2008年1月-2008年12月临床送检标本中鲍曼不动杆菌检出及耐药情况并分析。结果共检出185株鲍曼不动杆菌,其中138株来自痰标本占74.6%。具重耐药,对头孢菌素类耐药率超过50%,对氨基糖甙类超过70%,对亚胺培南、左氧氟沙星尚有较高的敏感率（分别为71.4%和66.7%）。结论鲍曼不动杆菌耐药性监测可为临床合理用药提供依据。

Analysis of acinetobacter baumannii distribution and drug resistance in hospital

Objective To investigate the distribution and vicissitude of drug resistance of Aeinetobacter baumannii from January to December in 2008. Methods The date of acinetobacter baumannii infection and its drug resistance from pa- tients during the period of January to in 2008 were analyzed. Results 185 strains of acinetobacter baumannii were isolated from patients. The main infections were respiratory department （74.60%）. Imipenem and Levofloxacin showed better activity to acinetobacter baumannii （ 71.4% and 66.7% ）. Higher resistance rate were cephalosporin （ 〉 50% ） and amidocyanogen （ 〉 70% ） antibiotics. The strains displayed multi drug resistance. Conclusion We should be aware of importance of acineto- bacter baumannii infection and its drug resistance change, and provide basis for reasonable use of drugs in clinical practice.