| 2型糖尿病患者口服降糖药的成本-效果分析 |
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| 引用本文： | 季波,刘姗.2型糖尿病患者口服降糖药的成本-效果分析[J].临床合理用药杂志,2009,2(16):27-28. |
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| 作者姓名： | 季波 刘姗 |
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| 作者单位： | 广州军区广州总医院药学部,广州市,510010 |
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| 摘 要： | 目的比较7种治疗2型糖尿病药物的成本-效果。方法将235例2型糖尿病患者分成7组：马来酸罗格列酮（文迪雅）组29例（A组）;二甲双胍组54例（B组）;格列齐特（达美康）组40例（C组）;格列美脲组28例（D组）;格列喹酮（糖适平）组38例（E组）;阿卡波糖（拜糖平）组25例（F组）;阿卡波糖（卡博平）组21例（G组）,运用药物经济学成本-效果分析方法,对7组口服降糖药进行评价;并且同时做了敏感性分析。结果在2型糖尿病的治疗中,二甲双胍为疗效较好且最经济的方案。结论应选用安全、有效、费用合理的药物治疗2型糖尿病。
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| 关 键 词： | 药物经济学 成本-效果分析 2型糖尿病 降糖药 |
The cost-effectiveness analyze of oral hypoglycemic drugs in the treatment of type2 diabetes mellitus |
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| JI Bo,LIU Shan.The cost-effectiveness analyze of oral hypoglycemic drugs in the treatment of type2 diabetes mellitus[J].Chinese Journal of Clinical Rational Drug Use,2009,2(16):27-28. |
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| Authors: | JI Bo LIU Shan |
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| Institution: | JI Bo ,LIU Shan.( Department of Pharmacy, Guangzlwu General Hospital of Guangzhou Military Command, Guangdong, Guangzhou 510010, China) |
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| Abstract: | Objective To compare and analyze the cost-effectiveness of 7 different drugs in the treatment of type2 diabetes mellitus. Methods 235 cases with type2 DM were divided into 7 groups. According to the principle of pharmacological economy, cost-effectiveness analysis used, seven kinds of oral hypoglycemic drugs （ Group A ： rosigltazone maleate; Group B ： melfformin; Group C： gliclazide; Group D ： glimepiride; Group E ： gliquidone; Group F： axarbose ; Group G： glucobay） were com- pared; at the same time, sensitive analysis was performed. Results During the treatment of type2 diabetes mellitus, Mefformin is the cheapest drug and has better therapeutic effect. Conclusion The best drugs for type2 diabetes mellitus should be the one with safety,good efficiency and lower price. |
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| Keywords: | Cost -effectiveness analysis Pharmacological economy Type2 diabetes mellitus Hypeglycemic drug |
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