抗菌药物临床使用的药学干预和临床药学工作模式优化的效果分析

目的:分析临床药师药学干预对降低抗菌药物不合理使用率和使用强度的效果,规范抗菌药物的合理使用,探究建立临床药师与临床科室合作的工作模式。方法:抽取2015年1月-2018年3月间医院各科室住院患者抗菌药物临床使用资料为药学干预前组,统计与分析其抗菌药物不合理使用情况;另抽取应用PDCA循环管理后的2018年4月-2019年6月间医院各科室抗菌药物使用资料为药学干预后组;比较和分析两组不同季度抗菌药物使用强度,即DDDs/(100人·d)的差异;并针对不合理用药科室制定相应的专项整治计划和规范抗菌药物的合理使用,以降低抗菌药物使用强度。结果:应用PDCA循环管理后规范了医院抗菌药物的临床使用,降低了抗菌药物使用强度小于40 DDDs/(100人·d)。结论:临床药师通过药学干预抗菌药物的合理使用,加强和建立了临床药学知识教育培训、查房会诊和病历点评的工作模式,规范了抗菌药物的合理使用。

Analysis on Efficacy of Clinical Medication of Antibiotics for Pharmaceutical Intervention and Optimization of Working Mode of Pharmacy

Objective:To analyze the efficacy and intensity of pharmaceutical intervention by clinical pharmacists on reducing the unreasonable utilization rate of antibiotics,to standardize the rational medication of antibiotics and to explore the working mode of establishing cooperation between clinical pharmacists and clinical departments.Methods:The clinical use data of antibacterial drugs among inpatients in each department of the hospital from January 2015 to March 2018 were collected as the pre-pharmaceutical intervention group,and the unreasonable use of antibacterial drugs was statistically analyzed.In addition,the data of antimicrobial use in all departments of the hospital from April 2018 to June 2019 after the application of PDCA cycle management were extracted for the pharmaceutical intervention group.The intensity of antimicrobial use in two groups in different quarters were compared and analyzed,that is,the difference of DDDs/(100 persons·d).And for unreasonable drug use departments to develop the corresponding special rectification plan and the rational use of antibacterial drugs were standardized,reduce the intensity of the use of antibacterial drugs,so as to reduce the intensity of antimicrobial use.Results:After using of PDCA cycle management,the clinical medication of antibiotics in hospitals was standardized,and the intensity of antibiotics was reduced to less than 40 DDDs/(100 persons·d).Conclusion:Through pharmaceutical intervention in the rational use of antimicrobial drugs,clinical pharmacists have strengthened and established the working mode of clinical pharmacy knowledge education and training,ward rounds consultation and medical record review,and the rational medication of antimicrobial drugs was standardized.