超声检查和PET/CT检查诊断甲状腺乳头状癌中央区淋巴结转移的对比研究

目的比较超声检查和18F-FDG PET/CT检查对甲状腺乳头状癌中央区淋巴结转移的诊断价值。方法回顾性分析93例经病理证实的甲状腺乳头状癌患者中央区淋巴结转移情况,与术前超声检查和PET/CT检查对比,评价其诊断甲状腺乳头状癌中央区淋巴结转移的价值。结果超声检查诊断中央区淋巴结转移的敏感度、特异度、准确度、阳性预测值、阴性预测值分别是78.8%、61.0%、71.0%、71.9%、69.4%(χ^2=4.742,P=0.029);PET/CT检查诊断中央区淋巴结转移的敏感度、特异度、准确性、阳性预测值、阴性预测值分别是53.8%、78.0%、64.5%、75.7%、57.1%(χ^2=3.882,P=0.049)。超声检查和PET/CT检查诊断中央区淋巴结转移的ROC曲线下面积(AUC)分别为0.699、0.659。结论超声检查诊断甲状腺乳头状癌中央区淋巴结转移具有较高敏感度和准确性,且因其简便、分辨率高、无辐射等优势,较18F-FDG PET/CT检查更具有显著意义。

Diagnostic values of ultrasound and PET/CT in center lymph node metastasis on papillary thyroid carcinoma

Objective To evaluate the diagnostic efficacy of ultrasound and 18F-FDG PET/CT in center lymph node metastasis on papillary thyroid carcinoma.Methods A total of 93 patients with papillary thyroid carcinoma who had undergone total or subtotal thyroidectomy and center lymph node dissection were analyzed retrospectively.The receiver operating characteristic curve(ROC)was used to investigate the diagnostic values of ultrasound and 18F-FDG PET/CT.Results The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of ultrasound were 78.8%,61.0%,71.0%,71.9%,69.4%(χ^2=4.742,P=0.029),respectively.Those of 18F-FDG PET/CT were 53.8%,78.0%,64.5%,75.7%,57.1%(χ^2=3.882,P=0.049),respectively.The areas under the ROC curve(AUC)were 0.699,0.659,respectively.Conclusion Compared with 18F-FDG PET/CT,ultrasound has higher efficacy in diagnose of center lymph node metastasis on papillary thyroid carcinoma.