和而兼下法治疗小管间质性肾炎探讨

小管间质性肾炎(tubulointerstitial nephritis,TIN)常导致非少尿型或少尿型急性肾损伤,也是终末期肾脏病重要原因之一。本文认为TIN临床常见湿热、湿浊、瘀血阻滞气机,三焦枢机不利,升降逆乱,最终致上焦心肺气血壅滞,中焦失于和降,下焦气化失司;与肺、脾、肾受损及气血水运行失调相关,并据此提出和而兼下的基本治法,为临床提供一定参考。

Discussion on Treatment of Tubulointerstitial Nephritis with Reconciliation Combined Purgation Method

Tubulointerstitial nephritis(TIN)often leads to acute kidney injury of non-oliguria or oliguria type,which is one of the important causes of end-stage renal disease.This article believed that the stagnation of functional activities of qi with damp heat,damp turbidity and blood stasis,the abnormality of triple jiao and the disturbance of qi,were commonly seen in TIN,which would finally cause the qi and blood stagnation of the heart and lung in upper jiao,the failure of the descending of the stomach-qi in middle jiao,and the failure of qi-transforming function in lower jiao;these were related to the damage of the lung,spleen and kidney,and the imbalance of qi,blood and water operation.Therefore,the basic treatment of reconciliation combined purgation method was put forward,in order to provide certain references for clinical treatment.