超声引导下两种硬化剂药物治疗单纯性肝囊肿的疗效及并发症观察研究

背景近年来,超声介入技术发展迅速,超声引导下注射硬化剂治疗单纯性肝囊肿具有创伤小、并发症少、操作简便、疗效显著等优点,越来越受到临床重视,并成为单纯性肝囊肿的首选治疗手段.而其临床治疗效果与所使用的硬化剂种类密切相关.目的探讨超声引导下注射不同药物治疗单纯性肝囊肿的效果及其临床应用价值.方法回顾性分析我院收治的126例单纯性肝囊肿患者(共126个单纯性肝囊肿)的临床资料,按硬化剂药物不同分为聚桂醇组(63例,超声引导下注射聚桂醇治疗)和高渗葡萄糖组(63例,超声引导下注射高渗葡萄糖治疗),比较两组术中、术后1 mo的并发症情况以及术后3 mo的临床疗效.结果聚桂醇组治疗总有效率(98.41%)明显高于高渗葡萄糖组(73.02%),差异有统计学意义(P<0.05);聚桂醇组术后并发症总发生率(7.94%)明显低于高渗葡萄糖组(22.22%),差异有统计学意义(P<0.05).结论超声引导下注射硬化剂治疗单纯性肝囊肿疗效确切,而注射聚桂醇的疗效及安全性优于高渗葡萄糖,值得临床推广应用.

Efficacy and complications of ultrasound-guided injection of different sclerosing agents in treatment of simple hepatic cyst

BACKGROUND In recent years,ultrasound intervention technology has developed rapidly.Ultrasound-guided injection of sclerosing agent in the treatment of simple hepatic cyst has the advantages of less trauma,less complications,simpler operation,and significant effect,which has attracted more and more attention in clinical practice,and become the first-choice treatment for simple hepatic cyst.However,its clinical effects are closely related to the type of sclerosing agent used.AIM To investigate the clinical effects of ultrasound-guided injection of different sclerosing agents in the treatment of simple hepatic cyst.METHODS The clinical data of 126 patients with simple hepatic cyst(a total of 126 simple hepatic cysts)treated at our hospital were analyzed retrospectively.According to the sclerosing agent used,they were divided into either a polidocanol group(63 cases,ultrasound-guided injection of polidocanol)or a hyperosmolar glucose group(63 cases,ultrasound-guided injection of hyperosmolar glucose).The complications during operation and at 1 mo after operation,and the clinical effects at 3 mo were compared between the two groups.RESULTS The total effective rate(98.41%)of the polidocanol group was significantly higher than that of the hyperosmotic glucose group(73.02%)(P<0.05).The total incidence of postoperative complications(7.94%)of the polidocanol group was significantly lower than that of the hyperosmotic glucose group(22.22%)(P<0.05).CONCLUSION Ultrasound-guided injection of sclerosing agents in the treatment of simple hepatic cyst is effective,while the efficacy and safety of injection of polidocanol are better than those of hypertonic glucose.