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| 右心室流入道间隔部和右心室心尖部起搏神经内分泌激素和心功能的变化 | |
| 引用本文： | 张贵生,张婷婷,李隆贵.右心室流入道间隔部和右心室心尖部起搏神经内分泌激素和心功能的变化[J].临床荟萃,2011,26(2):96-99. |
| 作者姓名： | 张贵生 张婷婷 李隆贵 |
| 作者单位： | 1. 武警上海总队医院,心内科,上海,201103 2. 解放军三二二医院,超声科,山西,大同,037006 3. 第三军医大学新桥医院,心内科,重庆,630037 |
| 摘 要： | 目的探讨右心室流入道间隔部(RVIS)和右心室心尖部(RVA)起搏治疗缓慢性心律失常神经内分泌激素和心功能的变化。方法房室全能型起搏器(DDD)治疗患者106例,男86例,女20例,年龄45～86岁,平均(76.4±9.5)岁,随机分为右心室流入道间隔部起搏组(RVIS起搏组)56例,右心室心尖部起搏组(RVA起搏组)50例。两组心房电极均植入右心耳梳状肌内,RVIS起搏组心室电极植入右心室流入道间隔部、RVA起搏组心室电极植入右心室心尖部。分别观察两组在起搏器植入时、起搏3个月和6个月不同时期,血浆肾素活性(PRA)、血管紧张素Ⅱ(AngⅡ)、醛固酮(ALD)、心钠肽(BNP)和去甲肾上腺素(NE)等神经内分泌激素的含量;应用彩色多普勒超声心动图测定:心排血量(CO)、每搏输出量(SV)、射血分数(EF)和左心室舒张末内径(LVDd)。结果 RVA起搏组治疗后,血浆PRA、AngⅡ、ALD、BNP和NE含量增加,而RVIS起搏组则明显下降;RVIS起搏组心功能改善明显:CO、SV和EF值明显增加,LVDd值缩小,RVA起搏组SV、EF值下降,LVDd增加,CO虽然有所增加,但不如RVIS起搏组明显,差异均有统计学意义(P<0.05)。结论 RVIS起搏优于RVA起搏,可明显改善心功能,纠正神经内分泌激素失调,值得临床推广。 |
| 关 键 词： | 心律失常 心脏起搏 人工 激素类 心功能 |
Changes of neuroendocrine hormone and cardiac function in patients treated by right ventricular inflow tract pacing or rght ventricular apical pacing |
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| ZHANG Gui-sheng,ZHANG Ting-ting,LI Long-gui.Changes of neuroendocrine hormone and cardiac function in patients treated by right ventricular inflow tract pacing or rght ventricular apical pacing[J].Clinical Focus,2011,26(2):96-99. | |
| Authors: | ZHANG Gui-sheng ZHANG Ting-ting LI Long-gui |
| Institution: | ZHANG Gui-sheng1,ZHANG Ting-ting2,LI Long-gui31.Department of Cardiology,Shanghai Corps Hospital,Chinese People's Armed Police Forces,Shanghai 201103,China,2.Department of Ultrasonics,PLA322 Hospital,Datong 037006,3.Department of Cardiology,Xinqiao Hospital of the Third Military Medicine University,Chongqing 630037 |
| Abstract: | Objective To investigate the changes of neuroendocrine hormone and cardiac function in arrhythmia patients treated by right ventricular inlet septal(RVIS) pacing or right ventricular apical(RVA) pacing.Methods A total of 106 patients treated with DDD pacemaker:male 86 cases and female 20 cases,age 45-86 years,median 76 years,were randomly divided into two groups:RVIS pacing group 56 cases,RVA pacing group 50 cases.In both groups,the atrial electrodes were implanted in the right atrial appendage comb muscles... |
| Keywords: | arrhythmia cardiac pacing artificial hormones cardiac function |
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