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呼气末正压通气治疗重型颅脑损伤后神经源性肺水肿的疗效观察
引用本文:杨锦平,何鹏,刘付军.呼气末正压通气治疗重型颅脑损伤后神经源性肺水肿的疗效观察[J].临床肺科杂志,2011,16(7):997-998.
作者姓名:杨锦平  何鹏  刘付军
作者单位:潮州,解放军第188医院神经外科,广东,521000
摘    要:目的探讨呼气末正压机械通气(positive end-expiratory pressure,PEEP)在救治重型颅脑损伤后神经源性肺水肿(neurogenic pulmonary edema,NPE)中的作用。方法对28例重型颅脑损伤并发神经源性肺水肿患者进行常规机械通气,并设对照组;应用PEEP治疗后设置为治疗组,进行肺部啰音、RR、PaO2、SaO2、PaCO2比较。结果 PEEP治疗2 h后,26例患者双肺湿啰音明显减少甚至消失,RR、PaO2、SaO2改善具有极显著性差异(P〈0.001)。结论机械通气加用PEEP治疗重型颅脑损伤后NPE能在短时间内明显提高PaO2,是目前治疗NPE最有效的方法之一。

关 键 词:颅脑损伤  神经源性肺水肿  机械通气

Observation of curative effect in the treatment of neurogenic pulmonary edema after severe craniocerebral trauma by positive end-expiratory pressure mechanical ventilation
YANG Jin-ping,HE Peng,LIU Fu-ju.Observation of curative effect in the treatment of neurogenic pulmonary edema after severe craniocerebral trauma by positive end-expiratory pressure mechanical ventilation[J].Journal of Clinical Pulmonary Medicine,2011,16(7):997-998.
Authors:YANG Jin-ping  HE Peng  LIU Fu-ju
Institution:YANG Jin-ping,HE Peng,LIU Fu-ju Department of Neurosurgery,the 188th Hospital of PLA.GuangdongChaozhou 521000.
Abstract:Objective To investigate the role of positive end-expiratory pressure(PEEP) mechanical ventilation in the treatment of neurogenic pulmonary edema(NPE) after severe craniocerebral trauma(CCT).Methods 28 cases of severe CCT patients complicated with NPE were treated by conventional mechanical ventilation,and taken as control group.By applicating PEEP after the normal treatment,the treated group was compared to the control group in pulmonary rale,RR,PaO2,SaO2,PaCO2.Results 2 h after PEEP ventilation,moist rale...
Keywords:Craniocerebral trauma  Neurogenic pulmonary edema  Mechanical ventilation  
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