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乙型肝炎病毒感染对孕妇妊娠晚期血清甘胆酸的影响
引用本文:李映菊,刘映霞,唐爱琼.乙型肝炎病毒感染对孕妇妊娠晚期血清甘胆酸的影响[J].中国现代医学杂志,2008,18(3):367-369.
作者姓名:李映菊  刘映霞  唐爱琼
作者单位:1. 南华大学附属第一医院,感染科,湖南,衡阳,421001
2. 南华大学附属第一医院,妇产科,湖南,衡阳,421001
摘    要:目的通过检验乙型肝炎病毒(HBV)感染孕妇妊娠晚期的血清甘胆酸,探讨HBV感染对孕妇妊娠晚期的临床意义。方法以218例HBV感染的孕妇为实验组,120例健康孕妇为对照组,检测两组孕妇妊娠晚期空腹血清的甘胆酸值。并观察两组孕妇妊娠期发生肝内胆汁淤积症、胎儿宫内窘迫的情况。结果实验组血清甘胆酸明显高于对照组,差异有显著性(P〈0.01)。实验组肝内胆汁淤积症和胎儿宫内窘迫发生率明显高于对照组,且随着血清甘胆酸的升高,肝内胆汁淤积症和胎儿宫内窘迫发生率亦升高。结论HBV感染孕妇妊娠晚期检测血清甘胆酸值,对妊娠晚期孕妇及胎儿的监护有重要意义。

关 键 词:乙肝病毒  血清甘胆酸  肝内胆汁淤积症  胎儿宫内窘迫  乙型肝炎  病毒  感染  晚期孕妇  妊娠晚期  血清甘胆酸  影响  pregnant  women  late  acid  serum  infection  监护  胎儿宫内窘迫  检测血清  发生率  差异  结果  情况  肝内胆汁淤积症
文章编号:1005-8982(2008)03-0367-03
收稿时间:2007-07-12
修稿时间:2007年7月12日

Effect of HBV infection on serum glycocholic acid in late pregnant women
LI Ying-ju,LIU Ying-xia,TANG Ai-qiong.Effect of HBV infection on serum glycocholic acid in late pregnant women[J].China Journal of Modern Medicine,2008,18(3):367-369.
Authors:LI Ying-ju  LIU Ying-xia  TANG Ai-qiong
Institution:LI Ying-ju1,LIU Ying-xia1,TANG Ai-qiong2 (1.Department of Infectious Diseases,2.Department of Gynecology , Obstetrics,the First Affiliated Hospital of Nanhua University,Hengyang,Hunan 421001,P.R.China)
Abstract:Objective To investigate the effect of HBV infection on serum glycocholic acid in late pregnant women. Methods The level of serum glycocholic acid in late pregnancy were measured in 218 patients with HBV infected and 120 healthy control subjects. Intrahepatic cholestasis of pregnancy and intrauterine distress were observed in the two groups. Result The levels of serum glycocholic acid were significantly higher in HBV infected groups(P<0.01). The incidence of ICP and fetal distress in uterus were significant...
Keywords:hepatitis b virus(HBV)  serum glycocholic acid(SCG)  intrahepatic cholestasis of pregnancy(ICP)  intrauterine ditress(fetal distress in uterus)  
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